Genetic counseling now recommended for children with sarcoma

If your son or daughter has been diagnosed with a type of sarcoma – a tumor in connective tissue like muscles or bones – there are many questions: Will my child make a full recovery? What are the immediate and long-term side effects of treatment?

Most parents don’t consider whether their child will face a second cancer later in life.

However, a link between sarcomas and Li-Fraumeni syndrome, a rare condition that raises a person’s risk of developing one or more cancers to as high as 85 percent, has led genetic specialists at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center to recommend that all child sarcoma patients be offered genetic counseling for Li-Fraumeni syndrome. 

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Obesity and Cancer: What’s the Link?

There are a lot of good reasons not to gain too much weight, but you might not be aware of this one: Growing evidence links obesity to a higher risk of developing cancer, and being overweight may worsen a cancer patient’s outlook.

Although more and more studies are finding this connection, scientists haven’t uncovered the biological mechanisms by which excess pounds make normal cells more likely to turn cancerous. But they are pursuing a large number of leads, some of which may uncover new ways of fighting cancer – including losing weight.

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What do you say when a friend has cancer?

A year ago today, I went to see my doctor about a lump that was growing scarily fast inside my mouth. Twelve days later, I was in a hospital bed with a cocktail of chemo drugs moving through an IV in my arm.

Over the next few weeks, I adjusted to the fact that I had squamous cell carcinoma; that it was most likely curable; and that I had a long road of chemotherapy and radiation ahead.

But one thing I couldn’t get used to was telling people I had cancer.

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HPV linked to head and neck cancer

Traditionally, patients with oral cancers tended to be older individuals with a long history of smoking and heavy alcohol use. In the past decade, however, that picture has changed dramatically.

Today, infection with the human papillomavirus (HPV) is the leading cause of oropharyngeal cancer in the U.S. and Western Europe. Oropharyngeal cancers affect the back of the throat (i.e. the tonsils and base of the tongue). HPV is the same virus that causes most cases of cervical cancer in women.

Patients with HPV-related head and neck cancers are often relatively young, not heavy drinkers or smokers, and come from all segments of society.

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Do Viruses Cause Cancer?

Today, it is estimated that viruses are responsible for almost 20 percent of cancer cases worldwide. Seven viruses have been connected to specific types of malignancies.  They include: Human papillomaviruses (HPVs), a group of more than 150 related viruses that are spread by contact.  At least a dozen of them are known to cause cancer, … Read more

Blood cancer research may lead to new treatments

At this year’s American Society of Hematology Annual Meeting, Dana-Farber scientists presented major findings that could one day improve diagnosis and treatment of blood cancers, extend life, or even cure some diseases. Among the highlights: Steven Treon, MD, PhD, and his colleagues identified a gene mutation that underlies the vast majority of cases of Waldenström’s … Read more

Breast cancer specialist discusses treatment advances

Harold J. Burstein, MD, PhD, a Dana-Farber breast cancer specialist, discusses some of the important studies presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The five-day meeting includes more than 1,000 scientific presentations, seminars, and posters, with a focus on emerging treatments in hard-to-treat populations, patients with metastatic breast cancer, and breast cancer … Read more

Breast cancer patient honors her compassionate doctor

Ann Partridge, MD, MPH, was instrumental in the founding of Dana-Farber’s Program for Young Women with Breast Cancer, part of the Susan F. Smith Center for Women’s Cancers. The program, which focuses on the unique needs of breast cancer patients under 40, helps patients access fertility, genetic screening, and counseling services. Dr. Partridge was recently … Read more