What Is the Blood-Brain Barrier and How Does it Affect Brain Tumor Treatment?

The blood-brain barrier surrounds the brain and prevents harmful toxins and bacteria in the blood stream from entering the vital organ. What evolved as a life-saving defense, however, also blocks many drugs from reaching the brain, creating a major problem in treating brain tumors. The blood-brain barrier is formed by tightly-packed cells lining the walls … Read more

What Is Hormone Therapy?

Hormone therapy might more accurately be called anti-hormone therapy because it works by blocking hormones that spur certain cancers to grow. Hormones act by attaching to proteins, called receptors, on the outside of cells, resulting in cell or cancer growth. Reducing this type of cancer cell growth by blocking hormones is used most commonly in … Read more

Cancer Conversations Podcast – Episode #7: Life After Childhood Cancer Treatment

While the end of active cancer treatment may bring some relief, it can also bring many questions and anxieties for young patients and their families. In this Cancer Conversations podcast episode, Lisa Diller, MD, chief medical officer of the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, discusses topics around fertility, growth, late effects of treatment, … Read more

Can Detoxing Regimens and ‘Cleanses’ Fight Cancer?

If you type “detox and cancer” into an Internet search engine, you’ll get an avalanche of websites, articles, products, patient testimonials, and practitioners claiming that cancer can be prevented or even cured by diets or “cleanses” that rid the body of “toxins.” Are these approaches safe? Are they effective? It’s not necessarily as straightforward as … Read more

Cancer Conversations Podcast – Episode #5: What’s New in Metastatic Breast Cancer Treatment and Research

Although there is no cure for metastatic breast cancer, new developments in treatment and research are helping patients live longer and experience a better quality of life. In this Cancer Conversations podcast episode, Eric Winer, MD, director of Breast Oncology Program in the Susan F. Smith Center for Women’s Cancers at Dana-Farber, discusses the latest … Read more

The Latest Research and Treatment for Adult Brain Tumors

Historically, brain tumors have been some of the most challenging types of cancers. A protective barrier around the brain—called the “blood-brain barrier”—can prevent cancer treatments from reaching the tumor. Recently, increased interest in immunotherapy has given new hope to getting through this barrier. “We know the immune system can get into the brain to fight … Read more

How Long Does Radiation Stay in Your Body After Treatment?

Along with surgery and chemotherapy, radiation therapy has long been a mainstay of cancer treatment. It uses high-energy waves or particles such as x-rays, gamma rays, electrons, or protons to destroy or damage tumor cells. Radiation creates small breaks within the DNA of cancer cells, preventing the cells from growing and dividing, and often causing … Read more

What Are the Side Effects of Immunotherapy?

Medically reviewed by Gordon Freeman, PhD New drugs that stimulate the patient’s immune system to attack tumors have achieved some dramatic and long-lasting benefits in several forms of cancer. A few drugs are already approved for wide use and many more are in the research pipeline. Because these immunotherapy agents work differently than chemotherapy, the … Read more

What A Cancer Cure ‘Moon Shot’ Might Look Like

This post originally appeared on WBUR’s CommonHealth blog. By Barrett Rollins, MD, PhD President Obama’s call for a new national effort against cancer – a “moon shot” – comes at a most opportune time. Cancer research has advanced significantly and now genomic analysis of individuals’ tumors can reveal the specific DNA changes that drive cancer … Read more

How Can We Make Personalized Therapy for Childhood Cancer a Reality?

This blog post originally appeared on Vector, Boston Children’s Hospital’s science and clinical innovation blog. By Tom Ulrich For some pediatric cancers, such as acute lymphoblastic leukemia, older forms of therapy — and older ways of defining who receives which therapy — have served well over the last few decades. But that approach is no longer … Read more

Can Cancer Patients Participate in More Than One Clinical Trial at a Time?

Clinical trials are a key part of medical science’s effort to improve treatments for cancer patients. There are a variety of different types of trials, including therapeutic clinical trials, which test the safety and effectiveness of potential new agents in patients. Some patients participate in several therapeutic clinical trials, in succession, over the course of … Read more

How Medications for Mood and Anxiety Can Benefit Cancer Patients

By Fremonta Meyer, MD Many people – cancer patients and others – have fears and misconceptions about taking medication to manage their mood, reduce anxiety, and treat conditions such as depression. Some believe taking medication for psychological reasons means they are weak, while others fear they will get addicted to medication or that they will … Read more