New Online Tool Guides Genetic Testing for Lynch Syndrome

A new online assessment tool developed at Dana-Farber can help rapidly identify people who should undergo genetic testing for Lynch syndrome, an inherited disorder that greatly increases the lifetime risk of colorectal, endometrial, ovarian, stomach, and other cancers. An estimated 1 in 279 individuals – nearly a million people in the United States – carry … Read more

BRCA-Positive Mom Takes Control of Her Cancer Risk

After learning in December 2014 that her father was a carrier of the BRCA-1 gene, Katherine Saunders immediately knew she needed genetic testing. The 37-year-old mom of two had a 50-50 chance of inheriting the gene, which increases the risk of ovarian and breast cancers, and was likely responsible for the multiple breast cancer diagnoses in … Read more

The Genomics Behind Blood Cancers and Other Blood Disorders

Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring whether tumor DNA floating in … Read more

Cancer Conversations Podcast—Episode #14—The Latest in Genetics and Women’s Cancers

Advances in genetic research may improve the prevention, diagnosis, and treatment of women’s cancers. “More genes are being found and fewer families are having to wonder if there is something genetic that may increase their risk, or future generations’ risk, of developing cancer,” says Judy Garber, MD, MPH, director of the Center for Cancer Genetics … Read more

Family Ties: Why Genetics Matter

By Christine Hensel Triantos  On a cold winter day in 2002, Sharon Goyette stepped into Dana-Farber’s Center for Cancer Genetics and Prevention. She was a 21-year-old college student, and this was the last place she wanted to be. But her mother had insisted. After developing colon cancer, Goyette’s mother had been diagnosed with Lynch syndrome … Read more

Precision Medicine and the Future of Cancer Treatment

Precision medicine is rapidly changing the way cancer is studied and treated today. With new information about genetic and molecular characteristics in tumors, doctors are finding more effective and less toxic ways to fight the disease. “Precision medicine is seeing the monster of cancer clearly for the first time in a way that we can … Read more

Five Things You Need to Know About Cancer Genetics

Although most cancers are sporadic or occur by chance, a small percentage are due to inherited genetic (or germline) mutations, which can often be identified through genetic testing. These mutations are different from somatic mutations, which are not inherited, but occur during one’s lifetime. Profile, a research project launched by Dana-Farber and Brigham and Women’s Hospital, … Read more

Understanding Genomics and Cancer

If the new era of “targeted” cancer drugs and personalized treatments for patients realizes its promise, the power of genomics will get a lot of the credit. Genomics is one of the most commonly heard terms in cancer research and biotech companies today – but what does it really mean? What is genomics? Most people … Read more