Lymphoma: How do we treat it? Where are future therapies headed? On Wednesday, Dec. 18, Ann LaCasce, MD, of the Dana-Farber/Brigham and Women’s Cancer Center Adult Lymphoma Program will answer your questions about lymphoma care in a live video webchat. The 45-minute chat starts at 1 p.m. EST and will air live on Dana-Farber’s YouTube … Read more
Despite the research, the promising new drugs, the many ongoing clinical trials, lung cancer remains a disease that affects too many people, too often. For patients and family members, the disease carries an added burden: a stigma that lung cancer and smoking go hand in hand, and that lung cancer patients brought this on themselves. Not only must these patients and family members face their disease, but they also must carry the guilt and blame that some people cast their way.
When we posted a recent infographic on smoking and cancer, we unintentionally helped promote that stigma. We’re deeply sorry and have removed the infographic.
Stem cell transplantation (sometimes called bone marrow transplants) is a treatment for certain forms of cancer, such as leukemia, lymphoma, and multiple myeloma, as well as other diseases. But before a patient can receive a transplant, stem cells must be collected from a donor (an allogeneic donation) or from the patient (an autologous transplant).
As recently as five years ago, progress in treating life-threatening malignant melanoma was slow. Since then, several molecularly targeted drugs have burst on the scene, and new strategies for awakening the immune system to attack the cancer cells have yielded dramatic long-term survival benefits for some patients.
“The outlook for patients has never been so good – and we anticipate that in the next year or two it will be much better,” says Louise M. Perkins, PhD, chief science officer for the Melanoma Research Alliance, which funds research on the skin cancer.
“Clinical trials really are the future of lymphoma treatment,” says Ann LaCasce, MD, a medical oncologist in the Adult Lymphoma Program at Dana-Farber/Brigham and Women’s Cancer Center.
At 40-years old, Robach is among a population of younger women with breast cancer. According to the American Cancer Society, about 5 percent of all breast cancer cases in the United States occur in women age 40 and younger.
This Veteran’s Day, Dana-Farber thanks our patients, survivors, families, and friends who have served or are serving in the armed forces, including survivors Stacey Carroll, Ben Groen, and Tim Crowley, who tells his story below.
In June 2010, I was diagnosed with acute myeloid leukemia (AML), a fast-moving disease where too many immature white blood cells are present in the blood and bone marrow, after doctors found abnormalities in routine blood work for the Marines. My wife, Julie, and I were in shock. We had just celebrated Father’s Day with our two young children, Jack and Kate, and now we would be spending the foreseeable future at Dana-Farber/Brigham and Women’s Cancer Center.
There has been some uncertainty surrounding this question, but recent studies have demonstrated that having a vasectomy has no effect on the risk of prostate or testicular cancer.
Older data – from studies tracking disease rates across broad population groups – suggested a modest connection, while other studies found no such link.
Medically reviewed by Pasi A. Jänne, MD, PhD Lung cancer develops in the tissue of the lung, usually in the cells that line the air passages. Here are some common questions about the disease, answered by Pasi A. Jänne, MD, PhD, Director of Dana-Farber’s Lowe Center for Thoracic Oncology. What are the types of lung cancer? There are … Read more
Increasing evidence through research at Dana-Farber and elsewhere supports the use of acupuncture as a remedy for some of the symptoms breast cancer patients experience. This integrative therapy can be used in conjunction with radiation and chemotherapy.
Q: There seems to be some progress concerning treatment of brain tumors, especially immunotherapy. Do you think we will see further advancements in that area, or in other areas?
A:Immunotherapy is indeed a hot topic in gliomas. This is largely driven by advances we have seen in the treatment of melanoma. The way these drugs work is to release inhibition of the immune system so the immune cells can recognize cancer cells and attack the tumor. These advances are promising, and we hope this avenue of research will soon extend to gliomas. Development of trials in this direction is currently underway, and we anticipate the trials will open within the year or so.
In the last few years, we have seen a significant amount of progress in understanding glioma biology, including the mechanisms of tumor growth and resistance to treatments. Current research is focusing on treatment targeting specific pathways. It is difficult to envision which specific pathway or target will reveal the answer. It may be a combination of a few different targeted therapies, rather than one approach.
Breast cancer may develop in one part of the body, but it’s not just one disease. In fact, oncologists think of breast cancer as at least three different types of diseases.
Erica Mayer, MD, MPH
Triple-negative breast cancer (TNBC) describes breast cancer cells that do not have estrogen, progesterone, or HER2 receptors. It makes up approximately 15 percent of all breast cancers and is typically more aggressive than the other two types, estrogen receptor-positive breast cancer and HER2-positive breast cancer.
“It may be the smallest group, but TNBC still represents thousands of women with breast cancer, so it is a very important group for us,” says Erica Mayer, MD, MPH, a medical oncologist at Dana-Farber’s Susan F. Smith Center for Women’s Cancers.
Although there are two main types of cervical cancer, known as adenocarcinoma and squamous cell carcinoma, they’ve generally been treated as one disease, with the same approach to treatment. In a recent study, my colleagues and I surveyed the DNA in both types of cervical cancer cells to see if there were any differences. Such variations may help explain why the two types sometimes behave the way they do, and guide us toward treatments that work best in one type or the other.
Thyroid cancer is a disease in which malignant cancer cells form in the tissues of the thyroid gland. Like most forms of cancer, thyroid cancer can be broken down into several different types or subgroups, says Jochen Lorch, MD, director of Dana-Farber’s Thyroid Cancer Center. Most types of thyroid cancer are treatable and in some … Read more
When my son Ryan ran the Boston Marathon this year, I watched him with a special level of pride. Not only had he completed his first-ever marathon in four hours, but he was running, in large part, because of me.
A preventive (or prophylactic) mastectomy is the removal of a healthy breast to reduce the chances of developing breast cancer in that breast. A patient might consider a preventive mastectomy under different circumstances, including: There are many things to consider before deciding. Mastectomy is major surgery, so it is important to understand the risks and … Read more
Women who believe that drinking moderate amounts of alcohol won’t increase their risk of breast cancer may want to think again.
Last year, Wendy Chen, MD, of the Susan F. Smith Center for Women’s Cancers at Dana-Farber and her colleagues published a study showing that women who drank as little as three to six glasses of wine or other alcoholic beverages a week increased their breast cancer risk by about 15 percent.
