Dana-Farber Cancer Institute recently partnered with CancerConnect and Ursula Matulonis, MD, to answer questions about ovarian cancer. Experts in the Susan F. Smith Center for Women’s Cancers offer the latest research and treatment for this type of cancer. Watch one patient’s story.
Q: Is taking curcumin recommended to prevent ovarian cancer from returning? Do you have any other suggestions for preventing recurrence?
Testicular cancer is the most commonly diagnosed cancer in young men (ages 15-34). It is also one of the most treatable and curable types of cancers.
By Meg McCormick
When I learned I had a stage 4 breast cancer, I decided not let it rob me of the opportunities to enjoy my life. I still have a physically active, socially engaged lifestyle, and if you have metastatic breast cancer, so can you.
Lung cancer can be a frightening diagnosis. However, new treatment approaches and promising research trends have made the outlook for patients a little more optimistic, says David Jackman, MD, an oncologist in the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute.
While chemotherapy can kill cancer cells, certain chemotherapy drugs can also cause an uncomfortable and distressing condition that may produce numbness, tingling, and discomfort in the arms or legs. This condition, known as peripheral neuropathy (CIPN), can make it difficult for people to perform day-to-day activities.
Although there is no sure prevention for CIPN, there are ways to control the pain and minimize its effects on quality of life, says Cindy Tofthagen, PhD, ARNP, an assistant professor of nursing at the University of South Florida and post-doctoral fellow at Dana-Farber and the University of Massachusetts.
There are many decisions parents face after testing for genetic cancer risk, including whether to tell their children and how to approach the conversation.
If you decide to talk to your children about the test results, allow yourself some time to process the information; you want to be calm and clear when you talk with them. Remember that you know your children best and there are no set rules for talking to kids about genetic tests.
You also may want to talk with your spouse and decide whether you would like to speak with the children together or individually. It is good to be aware that sometimes spontaneous discussion opportunities arise – such as driving a child to school or practice – when a child asks a question that can disrupt parents’ plans for informing them, but can feel like a natural way for the topic to come up and be talked about.
After a long period of slow progress, new knowledge about the genetics of ovarian cancer is leading to the development and testing of new therapies.
Researchers at the Susan F. Smith Center for Women’s Cancers will soon be launching several phase 3 clinical trials testing drugs known as PARP inhibitors for patients with platinum-sensitive recurrent ovarian cancer – tumors that initially responded to platinum-based chemotherapy agents but have shown evidence of regrowth at least six months after treatment. Phase 3 trials test drugs in large numbers of patients to evaluate the drugs’ effectiveness as well as safety. PARP inhibitors work by blocking one of the pathways by which tumor cells repair their damaged DNA.
When Angelina Jolie underwent a preventative double mastectomy earlier this year, this issue of cancer risk and genetics made front-page headlines. Jolie, who announced the operation in a New York Times op-ed, tested positive for the BRCA1 gene mutation and learned she had an 87 percent risk of developing breast cancer.
Jolie’s announcement left many women wanting to know more: What is a gene mutation? Should I undergo genetic testing? What should I do if my tests are positive?
Medically reviewed by Ursula Matulonis, MD
By Maura Perkins
I can’t pinpoint when I started to get ovarian cancer symptoms. It was all very subtle and gradual. I was a healthy person. I ran, biked swam, hiked, and went to the gym regularly.
A slight pain in my left side, difficulty digesting food, feeling of fullness, and shortness of breath: those were the subtle constellation of symptoms that landed me in my primary care doctor’s office. At the age of 50, I felt like I was going downhill fast.
The 21st century has seen great strides in treatment for multiple myeloma, a cancer of the bone marrow once considered a death sentence. In fact, thanks to research by Dana-Farber scientists, this blood cancer that took the lives of Geraldine Ferraro and Leonard P. Zakim has become a chronic disease for many patients.
More than 70 years ago, two pharmacologists began looking at mustard gas as a possible treatment for lymphoma. The chemical, used during World War I, lowered blood counts and destroyed lymph nodes in soldiers who were exposed to the gas.
Two decades after the war, a thoracic surgeon named Gustav Lindskog used nitrogen mustard to successfully treat a patient with non-Hodgkin’s lymphoma.
The drug Avastin, when added to initial therapy for glioblastoma, can give patients a few extra months’ reprieve before their brain tumors start growing again, but does it make their quality of life better – or worse?
That’s a matter of heated debate for doctors – and confusion for patients – after two large clinical trials reported conflicting results at the annual American Society of Clinical Oncology (ASCO) conference in June. Some experts contend that Avastin lacked sufficient benefit for use as an “upfront” treatment for glioblastomas – the most common and aggressive brain tumors.
A diagnosis of ovarian cancer can raise a lot of questions. It can also raise many new medical terms, which your doctor or a member of your care team can explain. Here are some terms to know. What are the types of ovarian cancer? Epithelial ovarian cancers These cancers, which account for the majority of ovarian cancers, … Read more
Palliative care is often misunderstood. People may associate it with end-of-life care or “giving up” – especially when facing a serious health challenge like cancer. But palliative care may not be what you think, and you shouldn’t be afraid to ask for it. Here’s a closer look at what palliative care is – and isn’t.
In January 2012, my wife and I had left Boston to spend a few months in sunny Florida. We had just passed Orlando when my cell phone rang. It was my primary care physician calling to tell me she was concerned that my PSA was elevated to 6, which showed that I did have a problem with my prostate.
This is where it all started.
Highly malignant brain tumors called glioblastomas are the most common primary cancer of the brain; about 11,000 cases are diagnosed every year in the United States. Patrick Y. Wen, MD (Director) and David Reardon, MD, (Medical Director) of the Center for Neuro-Oncology at Dana-Farber/Brigham and Women’s Cancer Center describe the efforts to improve care for these patients.
Actress Angelina Jolie is no stranger to the headlines, but she stunned the world with her Op-Ed in The New York Times, in which she shared her very private decision to have a preventive double mastectomy after testing positive for the BRCA1 gene mutation. “I hope that other women can benefit from my experience,” wrote Jolie. … Read more
Editor’s Note: This is the second in our series of stories celebrating Moms this Mother’s Day weekend. Yesterday, Michelle Maloney shared her story. Today, it’s Allison Bellevue’s turn.
By Christine Triantos
In one whirlwind year, Allison Bellevue moved to Boston, started a new job, met her future husband, and discovered she was pregnant. Compared to what followed, that year was a breeze.
When Bellevue, now 31, went for her first fetal ultrasound, doctors noticed a small mass on her right ovary. They told her it was likely a cyst, and they would keep an eye on it over time.
Millions of men each year have their blood tested to determine their levels of prostate specific antigen (PSA), a normal protein. Levels may be elevated in men with prostate cancer or other benign diseases of the prostate. However, experts have disagreed on who should be tested, when, and how frequently. Some are concerned about whether … Read more
Medically reviewed by Clare Sullivan, BSN, MPH, CRRN If you have your first chemotherapy appointment coming up, you’re likely thinking about a hundred things. If you’re also wondering about the logistics of it all, here are some practical tips for your first chemotherapy session, gathered from patients who have been there. Wear comfy clothes. Comfortable clothes … Read more