What is Paget Disease of the Breast?

Paget disease of the breast occurs when cancer cells within the breast grow along the sides of the milk ducts and exit onto the skin of the nipple and surrounding circle of skin called the areola. It can arise at any age associated with breast cancer and usually involves a single breast. Although the hallmarks … Read more

Care Team and Teammates Help Metastatic Breast Cancer Patient Stay Strong

As a multi-sport athlete growing up, Allison Rebello loved being part of a team. Today, living with metastatic breast cancer (MBC), she credits three teams for helping her stay active and optimistic in the face of an incurable but treatable disease. Rebello’s care team at Susan F. Smith Center for Women’s Cancers at Dana-Farber/Brigham and … Read more

Study Identifies Candidate Combinations for Triple-Negative Breast Cancer

In their quest for effective targeted therapies to treat triple-negative breast cancer (TNBC) — an aggressive disease that often doesn’t respond to standard chemotherapy — researchers at Dana-Farber and elsewhere have recently focused on the potential of drugs known as BET bromodomain inhibitors. BET inhibitors target a family of proteins including BRD2, BRD3, BRD4, and … Read more

What is a Lumpectomy?

There are many different treatment options available for breast cancer, including a type of surgery called a lumpectomy. While surgery can be anxiety-inducing, rest assured that lumpectomies are extremely safe and usually take no more than an hour. Here, Anna Weiss, MD, a breast surgeon in the Breast Oncology Program at the Susan F. Smith Center for Women’s Cancers at Dana-Farber/Brigham … Read more

Surgical Nurse Stays on Shift During Inflammatory Breast Cancer Treatment

As a nurse, Nadege Vilnaigre has devoted her professional life to helping those facing serious medical challenges. Her determination to stay on the job hasn’t waned — even in the face of her own experience with cancer. Vilnaigre is being treated at Dana-Farber for inflammatory breast cancer, which she was diagnosed with in September 2019. … Read more

Cancer Patient Faces Multiple Diagnoses with the Strength of a Warrior

One bout of cancer is enough to contend with, but since 2014 Mary Johnson has had to cope with four different cancers and related conditions. Despite these tests of her physical and emotional strength, Johnson is doing well today after treatment at Dana-Farber. “Coming to Dana-Farber gave me confidence because they supported me, and I … Read more

Focus is On Safety and Solidarity For Cancer Patients During COVID-19

Gina Solomon was in her office on March 10, worrying about the growing coronavirus pandemic, when the phone rang with news that quickly and dramatically shifted her concerns. Solomon, 55, learned she had HER2-positive breast cancer, a subtype of the disease that was as unfamiliar to her as COVID-19. In that instant, she went from … Read more

Living with Metastatic Breast Cancer: From a Sprint to a Marathon

When Kirsten Erlandsen was diagnosed with triple negative breast cancer in 2008, she approached her treatment like it was one of her road races. The mother of two knew that completing each treatment session brought her one stop closer to the “finish line” and her goal of becoming cancer-free. However, after a year of running … Read more

Young Investigators Use Patient Samples for Cancer Studies

In their search for better treatments for breast, ovarian, and other cancers, young investigators Jennifer Guerriero, PhD, and Sarah Hill, MD, PhD, rely on a precious commodity — patient tissue samples obtained by surgeons in Dana-Farber’s Susan F. Smith Center for Women’s Cancers. Studies of these normal and cancerous tissues, which are collected, banked, and … Read more

For Breast Cancer Patient, Positivity Is Everything

On a sunny July afternoon, Michelle Lemieux ran onto the field at Fenway Park to throw out the ceremonial first pitch during a Boston Red Sox home game. While the crowd of over 36,000 people continued to applaud as Lemieux ran back to her family, only a handful in attendance could truly appreciate what she … Read more

Young Mom with Metastatic Breast Cancer Fights for Other Patients

Julia Maues was excited to find out she was pregnant — and then she was diagnosed with breast cancer. She went through chemotherapy and delivered a healthy baby boy, but shortly after the birth, she learned that the cancer had spread throughout her body. She would need lifetime of treatment for metastatic breast cancer. The … Read more