Study Finds New Vulnerabilities in Diabetes-Associated Liver Cancer

Liver cancer that develops in people with obesity and Type 2 diabetes is dependent on elevated amounts of a protein that might be targeted for treatment by two existing drugs, say Dana-Farber scientists. The research reported in Cancer Research by Pere Puigserver, PhD, and colleagues pertains specifically to liver cancer in individuals who are obese … Read more

What is an Alpha-Fetoprotein (AFP) Tumor Marker Test?

Tumor markers are substances in the human body that are produced by tumors and secreted into the blood, urine, or other bodily fluids. Certain benign conditions can also raise these markers, but significant elevations or a progressive rise can indicate a malignant process.  An AFP, or alpha-fetoprotein, tumor marker test—one of many different types of … Read more

Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their position in the body, because … Read more

Signs and Symptoms of Liver Cancer [Infographic]

Primary liver cancer is cancer that forms in the tissues of the liver. Secondary liver cancer is cancer that spreads to the liver from another part of the body. Most liver cancer is secondary or metastatic. Primary liver cancer, which starts in the liver, accounts for about 2 percent of cancers in the U.S., but … Read more