Program Specializes in Older Adults with Gastrointestinal Cancers 

Dana-Farber’s Older Adult Gastrointestinal Cancer program specializes in treating patients who are 65 and older and have gastrointestinal cancers, such as colorectal cancer, esophageal and gastric cancer, liver cancer, neuroendocrine and pancreatic cancer.   “Older adults are richly complex and multidimensional,” says gastrointestinal and geriatric oncologist Nadine McCleary, MD, MPH, who leads the program. “They deserve … Read more

Study Finds New Vulnerabilities in Diabetes-Associated Liver Cancer

Liver cancer that develops in people with obesity and Type 2 diabetes is dependent on elevated amounts of a protein that might be targeted for treatment by two existing drugs, say Dana-Farber scientists. The research reported in Cancer Research by Pere Puigserver, PhD, and colleagues pertains specifically to liver cancer in individuals who are obese … Read more

What is an Alpha-Fetoprotein (AFP) Tumor Marker Test?

Tumor markers are substances in the human body that are produced by tumors and secreted into the blood, urine, or other bodily fluids. Certain benign conditions can also raise these markers, but significant elevations or a progressive rise can indicate a malignant process.  An AFP, or alpha-fetoprotein, tumor marker test—one of many different types of … Read more

Cancer Treatment: A Look at How It Has Evolved in 70 Years

In 1947, when Dana-Farber Cancer Institute founder Sidney Farber, MD, set out to find a drug treatment for childhood leukemia, cancer treatment took two forms – surgery to cut out cancerous masses, and radiation therapy to burn them out. Cancers that couldn’t be removed or irradiated – either because of their position in the body, because … Read more