New Options for First-Line Treatment of Chronic Lymphocytic Leukemia

Most patients with chronic lymphocytic leukemia (CLL) now have several options for first-line therapy, thanks to new clinical trial results and novel targeted agents. Many patients with CLL, a slowly progressive blood cancer in which the bone marrow makes too many white blood cells, don’t need immediate treatment but can be observed — sometimes for many years … Read more

What Does a Brain Tumor ‘Feel Like’?

We asked neuro-oncologists Lakshmi Nayak, MD, and Eudocia Quant Lee, MD, MPH, from Dana-Farber Cancer Institute’s Center for Neuro-Oncology, to review the red flags that warrant a medical follow up: Headaches that are new or worsening, especially in a person who doesn’t normally have headaches. Often they are worse when lying down and in the … Read more

What Are Precursor Blood Conditions and How Are They Treated?

Precursor conditions are early phases of diseases that may develop into cancers such as lymphoma, leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. Most people with precursor conditions do not experience symptoms, and since doctors rarely screen for these conditions, they are sometimes found through routine blood tests but often remain undiagnosed.  “Many diagnoses are purely incidental,” says Irene Ghobrial, MD, director … Read more

Living with Li-Fraumeni Syndrome is Using Knowledge as Power

Breast cancer survivor Jennifer Perry is at high risk of additional cancers during her lifetime because she carries an inherited mutation for Li-Fraumeni syndrome (LFS). But experts at the new Li-Fraumeni Syndrome and TP53+ Center at Dana-Farber Cancer Institute can help her manage that risk. While there is no treatment for LFS — a familial … Read more

Gynecologic Cancer Screening: What You Need to Know

Medically reviewed by Kevin Elias, MD Today, cervical cancer is the only type of gynecologic cancer for which there is a routine screening test. The lack of such tests for endometrial and ovarian cancer — the most common gynecologic cancers — makes it especially important that women and their doctors be attuned to the symptoms … Read more