Brain tumors , Immunotherapy
What’s New in Immunotherapy for Brain Tumors?

Vaccines, drugs, and modified human cells that activate the immune system against cancer have improved outcomes and prolonged lives in some types of cancer in the past few years. For patients with glioblastoma, the most common primary brain tumor in adults, immunotherapy has shown some promise in clinical trials — […]

October 6, 2017
0
Prostate cancer
Can Immunotherapy Be Used to Treat Prostate Cancer?

Prostate cancer can be treated by immunotherapy, and it was the first form of cancer for which a vaccine therapy – a treatment that stimulates the immune system to attack a disease – was approved by the U.S. Food and Drug Administration (FDA). That vaccine, called Provenge, was cleared by the […]

September 27, 2017
0
Immunotherapy , Lymphomas
How is Immunotherapy Used to Treat Lymphoma?

While new types of immunotherapy are being used to treat a wide variety of cancers, immunotherapy has been a front-line treatment for lymphoma for decades. Lymphoma occurs when white blood cells known as lymphocytes grow abnormally. There are nearly 70 subtypes of Hodgkin lymphoma and non-Hodgkin lymphoma that have been […]

September 14, 2017
0
Immunotherapy , Ovarian cancer , Uncategorized
Immunotherapy and Ovarian Cancer: An Update

By Ursula Matulonis, MD, Director, Gynecologic Oncology, Susan F. Smith Center for Women’s Cancers Immunotherapy has revolutionized the treatment of many types of cancer and is now undergoing testing in ovarian cancer. Clinical trials of drugs known as immune checkpoint inhibitors, which can unleash a potent immune system attack on […]

September 8, 2017
0
Immunotherapy , Uncategorized
Cancer Immunotherapy: Taking Aim with Neoantigens

It’s a compelling idea that has attracted scientists for decades: rather than poison tumors with chemicals and radiation, use a biological agent – a vaccine – to rally the body’s formidable immune defenders to kill cancer cells and shrink tumors. Yet, even as other forms of immunotherapy are showing promise […]

August 9, 2017
0
Care for adults , Colon Cancer , Rectal cancer
How Is Immunotherapy Used to Treat Colorectal Cancer?

Cancers of the colon and rectum haven’t yet been as effectively treated with immunotherapy as have melanoma and lung cancer, but researchers are increasingly identifying patients who do appear to benefit from the immunity-boosting drugs – and devising strategies they hope will expand the reach of immunotherapy in colorectal cancers. […]

July 14, 2017
0
Immunotherapy
Who Should Be Treated with Immunotherapy?

There has been much excitement in recent years around new drugs that exploit the power of the body’s immune system to fight cancer. In some patients, even with advanced cancers, these immunotherapy treatments have slowed or halted the disease after standard treatments no longer worked, with remissions lasting several years […]

July 6, 2017
0
Bladder cancer , Cancer research , Immunotherapy
How Is Immunotherapy Used to Treat Bladder Cancer?

Although immunotherapy seems like a recent phenomenon, physicians have been using the strategy to treat bladder cancer since 1990, when the BCG vaccine, made from a live but weakened tuberculosis bacilli, was approved for early stage cancer that hasn’t invaded the bladder’s muscular wall. Today, BCG is still the recommended […]

May 30, 2017
2
Brain tumors , Care for adults , Glioblastoma , Immunotherapy , Patient Stories, Adult
A Brain Tumor Kept at Bay by Immunotherapy

It’s 19 months after being diagnosed with the aggressive brain tumor, glioblastoma, and Andrew Wall is itching to go back to work as a police officer. “Sitting around is not my thing,” says Wall, 53, who hasn’t yet been cleared to return to work as a police officer in Monroe, […]

May 29, 2017
0
Immunotherapy , Melanoma , Patient Stories, Adult
Immunotherapy Gives Retired Dentist and Melanoma Patient a Reason to Smile

For nearly 50 years, Jay Schwab wondered whether the melanoma he survived as a young man would return in a more serious form. When it did, in 2016, Dana-Farber was ready with a revolutionary response. A retired pediatric dentist, Schwab is one of a growing number of Dana-Farber patients thriving […]

May 26, 2017
0
Cancer research , General interest , Immunotherapy
The Progress of Cancer Immunotherapy: The Tip of the Iceberg

If the human immune system was a powerful racing car, you could say that scientists in the past few years have gained unprecedented control over how to make it accelerate, and what causes it to slow or stop. This knowledge has spawned new immunotherapy drugs that are delivering dramatic benefits […]

May 9, 2017
2
Cancer research , Care for adults , Head and Neck Cancer , Immunotherapy
What’s New in Immunotherapy for Head and Neck Cancer?

For patients with advanced head and neck cancers, immune-based therapies have started to show results against these hard-to-treat tumors. Two immunotherapy drugs were approved in 2016 for use when standard treatments failed, and many other agents are being tested in clinical trials. Immunotherapies work by enhancing the body’s natural defenses […]

April 20, 2017
0
Cancer research , Hodgkin lymphoma , Immunotherapy , Lymphomas , Non-Hodgkin lymphoma
New Immunotherapy Therapy Approved for Lymphoma Patients

The Food and Drug Administration (FDA) approved a new kind of immunotherapy drug for adults and children with classical Hodgkin lymphoma who have relapsed after three or more prior lines of therapy. The approved drug, pembrolizumab (Keytruda), is part of a class of immunotherapy drugs called checkpoint inhibitors that block […]

March 28, 2017
0
Cancer research , Immunotherapy , Kidney cancer
What’s New in Immunotherapy for Kidney Cancer?

Kidney cancer is one of several cancers that has responded well to immunotherapy drugs, which can free the immune system from restraints that cancer cells can impose on it. The drug nivolumab (Opdivo), for example, which was recently approved, can extend survival in patients with metastatic kidney cancer after other […]

March 23, 2017
0
Cancer research , Immunotherapy , Melanoma
What’s New in Immunotherapy and Melanoma? [Webchat]

Cancer immunotherapy is a kind of cancer treatment that mobilizes the patient’s immune defenses to recognize and attack tumor cells. It is now the treatment of choice for many patients with advanced melanoma, according to Elizabeth I. Buchbinder, MD, a melanoma specialist at Dana-Farber. “Immunotherapy has taken off,” Buchbinder says, “There […]

March 14, 2017
0
Cancer research , Immunotherapy , Research
Can a Serum Biomarker Predict Response to Immunotherapy?

This post originally appeared on Cancer Research Catalyst, a blog from the American Association of Cancer Research (AACR). By Srivani Ravoori, PhD Immunotherapy, particularly a class of immunotherapeutics called immune checkpoint inhibitors, has transformed the treatment of several types of cancer in recent years. So far, the U.S. Food and […]

January 26, 2017
1
Cancer research , Gastrointestinal Cancer , Immunotherapy , Pancreatic cancer
Can Immunotherapy Help Patients with Pancreatic Cancer?

Patients with pancreatic cancer often ask Dana-Farber’s Brian Wolpin, MD, MPH, about immunotherapy, the rising star of cancer treatment that’s making impressive gains against many types of malignancies. Immunotherapy drugs, which mobilize the patient’s immune defenses to recognize and attack tumor cells, have worked against lethal cancers such as melanoma […]

November 30, 2016
0
Bladder cancer , Cancer research , Immunotherapy
Immunotherapy Beats Chemotherapy for Advanced Bladder Cancer Patients

The immunotherapy drug pembrolizumab (Keytruda) is the first therapy of any kind to improve survival in patients whose metastatic bladder cancer worsened after treatment with platinum-based chemotherapy. Keytruda proved so much better than chemotherapy in this “second-line” use that an international clinical trial was halted when the advantage became apparent. […]

October 21, 2016
0
Cancer research , Immunotherapy , Research
What’s New in Cancer Immunotherapy?

Keeping up with progress in the field of cancer immunotherapy requires paying close attention. The number of approved drugs that help the body’s immune system fight cancer continues to grow, as does the list of different cancers in which immunotherapy is proving effective – in some cases yielding dramatically longer-lasting […]

September 27, 2016
0
Cancer research , Immunotherapy , Melanoma , Research
ASCO 2016 Update: Immunotherapy and Melanoma

As one of the hottest topics in cancer research today, immunotherapy took center stage at the 2016 American Society of Clinical Oncology meeting in Chicago. Harold J. Burstein, MD, PhD, a breast oncologist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber Cancer Institute, recently sat down with […]

June 15, 2016
1
Cancer research , Immunotherapy
How Scientists Aim to Expand Immunotherapy Options for Cancer Patients

This post also appeared on the NERD (Novartis Explores Research & Development) blog. By Eric Bender Fighting cancer with immunotherapy has revolutionized treatment for some patients. Emphasize “some.” For most patients, drugs targeting the immune system to attack their tumors aren’t an option. This could change in the near future. […]

April 14, 2016
0
Cancer research , Immunotherapy , Rectal cancer
Can We Treat Colorectal Cancer With Immunotherapy?

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research (AACR). It is posted here with minor edits. March is Colorectal Cancer Awareness Month. About 134,490 people are estimated to be diagnosed with and about 49,190 are expected to die from colorectal […]

March 21, 2016
0
Cancer research , Care for adults , Immunotherapy , Treatments and Procedures
What Are the Side Effects of Immunotherapy?

New drugs that stimulate the patient’s immune system to attack tumors have achieved some dramatic and long-lasting benefits in several forms of cancer. A few drugs are already approved for wide use and many more are in the research pipeline. Because these immunotherapy agents work differently than chemotherapy, they can […]

February 10, 2016
4
Cancer research , Cervical Cancer , Immunotherapy
Targeted Therapy, Immunotherapy Among Top Research Areas for Cervical Cancer

Cancers of the cervix are diagnosed in more than 12,000 women in the United States every year. Worldwide, the annual tally of new cases reaches more than half a million. The biggest advance against the disease in recent years has come in the area of prevention. Vaccination against the human […]

January 28, 2016
0
Cancer research , Care for adults , Immunotherapy , Melanoma
Remission of Jimmy Carter’s Melanoma Shows Potential of Immunotherapy for Cancer

Former President Jimmy Carter’s announcement earlier this week that he is free of the melanoma that had spread to his liver and brain may be the highest-profile example yet of the promise of a new form of cancer treatment that unleashes an immune system attack on the disease. Carter, 91, […]

December 11, 2015
1
Cancer research , Immunotherapy , Lung cancers
Immunotherapy and Lung Cancer: Exploring the Latest Research

The year 2015 marked a milestone in the treatment of lung cancer, with two new immunotherapy drugs approved for patients with advanced disease, bringing a new approach to this hard-to-treat cancer. Several other immunotherapy agents are also moving forward in clinical trials. In the past few years, scientists have found […]

November 18, 2015
1
Cancer research , Immunotherapy , Treatments and Procedures
Hot Topics in Immunotherapy and Targeted Therapy

This blog post is an excerpt from a Q&A posted on the Cancer Research Catalyst blog, the official blog of the American Association for Cancer Research. The interview was done with Dana-Farber’s Levi Garraway, MD, PhD, in advance of the International Conference on Molecular Targets and Cancer Therapeutics.   What […]

November 12, 2015
0
Immunotherapy , Pancreatic cancer , Uncategorized
Researchers Focusing on Early Detection, Immunotherapy for Pancreatic Cancer

The challenge with pancreatic cancer has always been to catch it early. Because of its subtle, variable symptoms, the disease often isn’t diagnosed until an advanced stage, when it is particularly difficult to treat. Researchers are investigating not only how to detect the disease earlier but also how to better […]

November 9, 2015
0
Cancer research , Immunotherapy , Melanoma , Research
FDA Approves Immunotherapy Drug Combination for Melanoma

This blog post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. By Karen Honey, PhD Last week, new ground was broken in the field of cancer immunotherapy when the U.S. Food and Drug Administration (FDA) approved the first cancer treatment to combine […]

October 6, 2015
0
Cancer research , Immunotherapy
What Is Cancer Immunotherapy?

Immunotherapy is a treatment that uses a patient’s immune system to fight diseases like cancer. This new area of treatment is one of the most promising areas of cancer research today. There are several strategies used in immunotherapy; some simply give the immune system a boost in order to have […]

June 25, 2015
4
Cancer research , Immunotherapy , Treatments and Procedures
Immunotherapy, Targeted Drugs, Brain Cancer Research Among Highlights at Cancer Meeting

Eagerly awaited new data from trials of immunotherapy drugs, vaccines to treat brain tumors, and improved treatments for blood cancers sparked waves of optimism at the year’s biggest cancer meeting. The 2015 annual meeting of the American Society of Clinical Oncology (ASCO) drew about 30,000 cancer specialists to Chicago May […]

June 5, 2015
0
Cancer research , Immunotherapy
How Does the Body’s Immune System Fight Cancer? (Immunotherapy)

Immunology is one of the most promising areas of cancer treatment today. Immunotherapy drugs, which use the patient’s own immune system to fight cancer cells, have been effective in treating several forms of the disease, including melanoma, prostate cancer, Hodgkin lymphoma, and certain types of brain tumors. The immune system […]

June 1, 2015
2
Cancer research , Immunotherapy
What is the Science of PD-1 and Immunotherapy?

This is a story about the velocity of an idea – a discovery whose potential to improve cancer treatment practically leapt from the test tube. The groundwork was laid in the 1990s, when scientists learned that human cells carry certain proteins on their surface that enable them to escape attack […]

May 13, 2015
1
Brain tumors , Cancer research , Immunotherapy
New Immunotherapy Vaccines Show Promise in Treating Brain Tumors

Researchers in Dana-Farber’s Center for Neuro-Oncology are now launching attacks on glioblastomas from a new angle – by turning the patient’s immune system against the cancer cells. Where targeted chemotherapy uses drugs to disable proteins that cancer cells need to grow, immunotherapy drugs stimulate the patient’s immune system to recognize and […]

January 19, 2015
0
Cancer research , Care for adults , Immunotherapy , Ovarian cancer
Immunotherapy, Ovarian Cancer Treatment Top List of 2014 Cancer Developments

Immunotherapy, treatments for ovarian cancer, and investigating game-changing drug therapies topped the list of the most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014. Here are some highlights from the last year in research: Hodgkin lymphoma Some of the most dramatic evidence of potential of immunotherapies […]

December 31, 2014
0
Chemotherapy , General interest , Immunotherapy
How Does Chemotherapy Work? Including Oral Chemotherapy and Immunotherapy

More than half of all people with cancer will get chemotherapy – powerful drugs that kill cancer cells to cure the disease, slow its growth, or reduce its symptoms. There are more than 100 different drugs used in chemotherapy, sometimes alone, but more often in combinations that have proven effective […]

November 10, 2014
5
Cancer research , Immunotherapy , Melanoma
Keytruda: New Immunotherapy Drug for Melanoma Wins FDA Approval

The Food and Drug Administration has approved a new type of  immunotherapy drug that will provide a much-needed option for patients with advanced or inoperable melanoma who no longer respond to other drugs – including the immunotherapy agent ipilimumab (Yervoy). The drug, pembrolizumab or MK-3745, will be marketed under the name  Keytruda. Based on […]

September 5, 2014
4
Cancer research , Immunotherapy , Treatments and Procedures
Cancer Immunotherapy Named ‘Breakthrough of the Year’

By Robert Levy Treatments that unleash the body’s own disease-fighting cells against cancer – an approach known as immunotherapy – have been heralded as the “Breakthrough of the Year” by Science magazine.

December 24, 2013
22
Cancer research , Immunotherapy
What is immunotherapy for cancer?

Immunotherapy is one of the most technologically advanced yet basic forms of cancer treatment. It uses the body’s own defense mechanism, the immune system, to fight cancer. Immunotherapy is probably most familiar to you in the form of vaccinations for the flu, polio, chicken pox, and other contagious diseases. In […]

June 5, 2012
0
Leukemias, childhood , Research
What’s New in Treatment for Pediatric Acute Lymphoblastic Leukemia (ALL)?

Acute lymphoblastic leukemia (ALL) is a type of leukemia in which a group of white blood cells, called lymphocytes, are affected. Leukemia is the most common form of cancer in children, and about 80 percent of children with leukemia have acute lymphoblastic leukemia. Chimeric antigen receptor (CAR) T-cell therapy was approved […]

October 5, 2017
0
Ovarian cancer
Testing a New Option in Ovarian Cancer Prevention

For women who inherit a breast and ovarian cancer susceptibility gene like mutant BRCA-1 or BRCA-2, the risk of ovarian and tubal cancers begins to rise significantly at age 40 to 45. Women at this age — and younger — are often advised to have their ovaries and tubes removed […]

September 29, 2017
0
CAR T-cell therapy , Lymphomas , Non-Hodgkin lymphoma
Non-Hodgkin Lymphoma: What’s New in Treatment? [Webchat]

Non-Hodgkin lymphoma is one of the two major subtypes of lymphoma, and about 72,000 people will be diagnosed with this cancer by the end of 2017, according to the American Cancer Society. There are more than 50 types of non-Hodgkin lymphoma – including B-cell and T-cell lymphomas, as well as […]

September 26, 2017
0
CAR T-cell therapy , Patient Stories, Adult , Research
CAR T-Cell Therapy Gives Cancer Patients New Hope

Judy Wilkins tried four different chemotherapy regiments over 18 grueling months to try to put her lymphoma into remission. Her team never could. But thanks to CAR T-cell therapy, an emerging immunotherapy treatment that is showing great promise in clinical trials nationwide, Wilkins is cancer-free. CAR (Chimeric Antigen Receptor) T-cell therapy […]

September 19, 2017
1
CAR T-cell therapy , Stem cell/Bone marrow transplant
Stem Cell Transplants and Cellular Therapies: What’s the Difference?

Donor stem cell transplants and other cellular therapies are treatment approaches that harness the immune system to fight cancer using cells from the patient or from healthy donors. Stem cell transplants are used to treat blood-related cancers such as leukemia, lymphoma, and multiple myeloma, as well as certain non-cancerous blood […]

September 7, 2017
0
CAR T-cell therapy , Leukemias, childhood
FDA Gives First-Ever Approval to CAR T-Cell Therapy

The Food and Drug Administration (FDA) announced today that a drug called CTL019 has become the first chimeric antigen receptor (CAR) T-cell therapy approved to treat a form of cancer. The decision means the drug can be used as standard therapy for the treatment of pediatric and young adult patients with […]

August 30, 2017
0
Acute lymphoblastic - ALL , CAR T-cell therapy , Non-Hodgkin lymphoma , Research
What Are The Side Effects of CAR T-Cell Therapy?

CAR T-cell therapy is a form of immunotherapy in which patients’ T cells are modified to become better at tracking down and destroying tumor cells. CAR T cells are made by extracting thousands of a patient’s T cells, sending them to a lab where they’re outfitted with genes and proteins […]

August 17, 2017
0
Brain tumors , Glioblastoma , Patient Stories, Adult
For Mother and Son, Brain Cancer Treatment Is All In The Family

Upon learning she had brain cancer in early 2016, Connie Etheridge immediately thought, “Thank goodness it’s me, and not my children.” Then, three months later, her son Trevor, 23, found out he too had brain cancer. It was a devastating double diagnosis, but the Etheridges have been by each other’s […]

August 15, 2017
0
Breast cancer
The Latest in Triple Negative Breast Cancer [Webchat]

Triple-negative breast cancer (TNBC), which makes up about 10 to 15 percent of all breast cancers, describes breast cancer cells that do not have estrogen, progesterone, or HER2 receptors. In a recent Facebook Live webchat, Ann Partridge, MD, MPH, Director of the Program for Young Women with Breast Cancer in the Susan […]

August 7, 2017
0
General interest
Deciding to Make a Change in Cancer Treatment

The first treatment a patient receives for cancer is generally the one his or her oncologist believes has the best chance of curing the disease or holding it in check. But the time may come when it may be appropriate to make a change in the therapy. In the best […]

July 24, 2017
1
General interest , Melanoma , Risk and Prevention
Is There a Connection between Cancer Medications and Increased Sunburn Risk?

By Nicole LeBoeuf, MD, MPH, clinical director of Dana-Farber’s Center for Cutaneous Oncology  While many people know that traditional chemotherapy drugs can increase sensitivity to the sun, some of the newer targeted therapies do as well. In fact, the risk of sun-related skin damage may be even higher with certain targeted […]

July 18, 2017
0
Care for adults
What Is Brain Metastasis and How Is It Treated?

When cancer spreads from its original site to the brain, it’s known as brain metastasis. While a significant percentage of all patients with cancer develop brain metastases, the most common cancers to spread to the brain are lung, breast, melanoma, colon, and kidney tumors. Every year, an estimated 100,000-400,000 people […]

July 17, 2017
0
Cancer research , Immunotherapy
What’s New in Treatment of Adult Histiocytic Disorders?

While blood cancers known as adult histiocytic disorders are very rare and many patients do well with today’s treatments, researchers are working to improve outcomes with therapies targeted to newly discovered mutations – and they are about to begin testing immunotherapies, too. Histiocytic disorders involved overproduction of immune white cells, […]

June 29, 2017
0
Cancer research , Immunotherapy
In Check: Attacking Cancer from Many Fronts

As a pediatric dentist, Jay Schwab had a clear-cut enemy: dental disease in children and adolescents, and the apprehensions they faced in the dental environment. Cavities could neither hide from his drill nor fool his X-ray machine, and plaque could easily be scraped away. Generations of patients went away smiling […]

June 27, 2017
0
General interest , Health Topics
How to Minimize Heart Problems Following Cancer Treatment

As more people are surviving cancer than ever before, greater attention is being focused on the cardiotoxicity of therapies and their long-term effects on the heart. Radiation therapy and a number of commonly used chemotherapy drugs can impair heart function, says Anju Nohria, MD, a cardiologist who leads the cardio-oncology […]

June 26, 2017
1
Cancer research , CAR T-cell therapy , Immunotherapy , Research
Catch Me if You Can: Finding Cancer Cells that Hide in Plain Sight

In the high-stakes contest of hide-and-seek between cancer cells and the human immune system, the advantage doesn’t always lie with the body’s defenders. A new approach to treatment, known as CAR T-cell therapy, may shift that balance of power. Cancer cells conceal themselves from the immune system not by barricading […]

June 21, 2017
0
Care for children
College Student Reconnects with the Oncologist Who Saved Her Life

This post originally appeared on Thriving, the Boston Children’s Hospital blog. Anna Protsiou was 5 when she was diagnosed with neuroblastoma in 2002. She remembers pain, and fruit-scented anesthesia masks that led her to stop eating cherries. She also remembers hospital arts and crafts projects. What she barely remembers is […]

June 20, 2017
0
General interest
What’s the Difference between Chemotherapy Drugs and Antibody Drugs?

Both chemotherapy and antibody agents are used in the treatment of cancer. In its broadest definition, cancer chemotherapy refers to any drug that destroys cancer cells or slows their growth and reproduction. As the “chemo” in their name suggests, however, true chemotherapy agents consist of chemicals that kill fast-growing cancer […]

June 9, 2017
0
Cancer research , CAR T-cell therapy , General interest
CAR T-Cell Therapy: How Does It Work?

CAR T-cell therapy is a kind of cellular therapy, which uses a patient’s own immune system cells to rally an attack on cancer. They’re made by removing a specific set of cells from the blood, modifying them in a lab to intensify the immune system’s natural response to cancer, and […]

June 2, 2017
2
Brain tumors , Brain tumors, childhood , Immunotherapy , Research
Webchat: The Latest in Brain Tumor Research and Care

In honor of Brain Tumor Awareness Month, David Reardon, MD, and Patrick Wen, MD, of Dana-Farber’s Center for Neuro-Oncology, went live on Facebook to answer questions about brain cancer. The doctors discussed advice for brain tumor patients, answered audience questions, and described the difference between the two major categories of […]

May 26, 2017
0
Brain tumors, childhood , CAR T-cell therapy , Care for children , Childhood
What’s New in Pediatric Brain Tumor Research and Care?

Mark W. Kieran, MD, PhD, director of Pediatric Medical Neuro-Oncology at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, spoke to pediatric patient families in a recent Facebook Live Webchat addressing pediatric brain tumor care. Kieran answered questions from audience members about the most common of the 300 brain tumor types […]

May 24, 2017
0
Bladder cancer , Genitourinary Cancer , Immunotherapy
What Are the Symptoms of Bladder Cancer?

Bladder cancer accounts for only five percent of new cancer cases in America – a small piece of the pie – but considering it is the fourth most common cancer in men, it is important to be aware of the signs and symptoms of this disease. The most common sign […]

0
Immunotherapy , Research
What Is a PD-L1 Test?

A PD-L1 test helps doctors determine whether a patient is likely to benefit from cancer drugs known as immune checkpoint inhibitors. It involves sending a piece of tumor tissue to a lab for analysis. PD-L1 is a protein that allows some cells to escape an attack by the immune system. Extending […]

May 22, 2017
2
Blood disorders, childhood , Cancer research , Patient Stories, Pediatric
How Pediatric and Canine Cancer Similarities Can Help Both Children and Pets

In March 2016, Ollie the pug, a therapy dog at Boston Children’s Hospital, paid a bedside visit to 7-year-old Carter Mock. Both dog and boy lost limbs to osteosarcoma, a cancer of the bone. Ollie’s left front leg was amputated at the shoulder. After removing the tumor in Carter’s left […]

May 2, 2017
0
Cancer research , Care for adults , Gastrointestinal Cancer , Pancreatic cancer , Precision Cancer Medicine
Attacking A Weak Point in Pancreatic Cancer’s Defense

In the fall of 2015, at the age of 44 – young for a person to be diagnosed with pancreatic cancer – Doron Broman was stunned to learn he had a large tumor on his pancreas that had metastasized to the liver. Facing only months to live, Broman would find […]

April 26, 2017
0
Blood Cancer , Cancer research , Leukemias , Lymphomas , Multiple Myeloma , Research , Stem cell/Bone marrow transplant
The Latest Advances Against Hematologic Cancers

Treatment of blood-related, or hematologic, cancers is seizing on insights into the basic genetic wiring of cancer cells and the body’s system for finding and attacking those cells. Research presentations at the annual American Society of Hematology (ASH) meeting in December gave evidence of how broad, and rapid, the progress […]

April 21, 2017
2
Care for adults , Kidney cancer
What Is Kidney Cancer?

Kidney cancer, or renal cancer, is a form of cancer in which cancer cells grow in the tissues of the kidneys. These two bean-shaped organs, located on each side of the body above the waist, are responsible for filtering and cleaning blood, removing waste, and producing urine. Kidney cancer generally […]

March 15, 2017
0
Breast cancer , Care for adults , Immunotherapy , Inflammatory breast cancer , Metastatic breast cancer , Susan F. Smith Center
Breast Cancer Treatment Yesterday and Tomorrow: A Long and Winding Road

Eric Winer, MD, director of Breast Oncology at Dana-Farber’s Susan F. Smith Center for Women’s Cancers, gave the William L. McGuire Memorial Lecture at the  San Antonio Breast Cancer Symposium in December 2016. This annual lecture and award are given to a breast oncologist who made significant contributions to the […]

March 3, 2017
2
Immunotherapy , Treatments and Procedures , Uncategorized
What’s New in Radiation Oncology? [Webchat]

At Dana-Farber, radiation oncologists like Dr. David Kozono, MD, PHD work to improve outcomes in cancer through research and deliver quality care to patients through radiation therapy. About two-thirds of cancer patients undergo radiation therapy as part of their treatment. What new developments are occurring in the world of radiation? […]

February 20, 2017
0
Biliary cancer , Gastrointestinal Cancer , General interest
What Is Biliary Cancer?

Biliary cancer is a form of cancer that develops in the bile duct system, which connects the liver, gallbladder, and small intestine, moving bile – a fluid that helps digest fats – to the small intestine. While relatively uncommon, approximately 15,000 people in the United States are diagnosed with this […]

February 10, 2017
0
Cancer research , Immunotherapy , Precision Cancer Medicine , Research , Risk and Prevention
Experts Forecast Cancer Research and Treatment Advances in 2017

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. It was originally published Jan. 10, 2017. By Srivani Ravoori, PhD As we step into 2017, a big question looming in the minds of all stakeholders in the cancer research arena is: […]

January 10, 2017
0
Cancer research , General interest
21st Century Cures Act Will Support ‘Revolutionary’ Cancer Research

On Dec. 13, President Barack Obama signed into law the 21st Century Cures Act, legislation that includes significant funding to the National Institutes of Health (NIH) to further the Beau Biden Cancer Moonshot, and to the Food and Drug Administration (FDA) to speed the drug approval process. Laurie Glimcher, MD, […]

December 14, 2016
0
General interest , Lung cancers
Olympian Aly Raisman Honors Grandmother with Support of Lung Cancer Research

Nurses at Dana-Farber are used to hearing patients gush about their children and grandchildren during chemotherapy treatments, but Stephanie Ann Benoit, RN, still smiles when recalling how Nancy Raisman sang the praises of her granddaughter. “Aly is going to be in the Olympics,” the lung cancer patient would say proudly, […]

November 24, 2016
0
Cancer research , Head and Neck Cancer , Immunotherapy
Use of Immunotherapeutic Expanded to Fifth Type of Cancer

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association of Cancer Research. It was originally published Nov. 15, 2016. By Karen Honey, PhD On Thursday, the U.S. Food and Drug Administration (FDA) announced that it had approved expanding the use of the immunotherapeutic nivolumab […]

November 15, 2016
4
Care for adults , Lung cancers , Patient Stories, Adult
Finding Happiness Despite Stage IV Lung Cancer

By Joann Totten As a non-smoker, I never imagined I would be diagnosed with stage IV lung cancer, let alone at age 50. But that’s what happened on Aug. 5, 2015, just six weeks after I started experiencing a non-productive cough. The doctors felt certain it was bronchitis, but as […]

November 14, 2016
1
General interest , Treatments and Procedures
What Is Combination Therapy?

Combination therapy, the use of more than one type of therapy in treating a patient, is a hallmark of cancer treatment. The complexity of the disease – its tendency to spread beyond its original site and become resistant to certain drugs, and its genetic diversity – underscores the need for […]

November 7, 2016
0
Care for children , Neuroblastoma, childhood , Patient Stories, Pediatric
Young Actor Plays Unexpected Role for Others with Neuroblastoma

Before he was diagnosed with neuroblastoma in 2014 at the age of 11, Noah Smith was a veteran of the children’s theater stage. The suburban Boston boy had been cast in ensembles. He’d played Kurt Von Trapp in “The Sound of Music.” Little did Noah know that he would soon […]

September 30, 2016
0
Cancer research , Ovarian cancer
Ovarian Cancer: State of the Science

By Ursula Matulonis, MD This is an exciting time for those of us engaged in research and patient care for ovarian cancer. As we’ve learned more about this cancer – its early formation, molecular machinery, and the body’s defenses against it – we’ve also come to understand its weaknesses. An […]

September 29, 2016
0
Brain tumors , Podcasts , Research , Treatments and Procedures
Cancer Conversations Podcast—Episode #17: The Latest in Brain Tumor Research and Treatment

Brain tumors can be among the most challenging cancers to treat. The blood-brain barrier, a natural defense mechanism that shields the brain from harm, can also prevent cancer treatments from reaching tumors. “It can be difficult to get treatments effectively into the brain,” says David Reardon, MD, clinical director of […]

September 9, 2016
0
Cancer research , Endometrial (Uterine) cancer
What is the Latest Research in Endometrial Cancer?

For endometrial cancer, as for virtually every form of cancer, advances in genomics are transforming the understanding and treatment of this disease, which arises in the lining of the uterus or womb. As part of the Profile research project at Dana-Farber, Brigham and Women’s Hospital, and Boston Children’s Hospital, investigators […]

August 30, 2016
0
Podcasts , Prostate cancer , Research , Treatments and Procedures
Cancer Conversations Podcast—Episode #16: The Latest in Prostate Cancer Treatment and Research

Prostate cancer affects 230,000 men each year. Although diagnoses are increasing worldwide, most people die with prostate cancer and not of prostate cancer, according to Mark Pomerantz, MD, a medical oncologist in Dana-Farber’s Lank Center for Genitourinary Oncology. In this Cancer Conversations podcast episode, Pomerantz discusses genetics, risk factors, and […]

August 26, 2016
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