Aspirin is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to reduce fevers and relieve mild to moderate pain deriving from muscle aches or strains, toothaches, headaches, and symptoms of the common cold. Research so far suggests that taking a small dose of daily aspirin over a period of years can reduce the risk … Read more
Normal human cells need just the right amount of oxygen — not too much nor too little — to survive and stay healthy. This critical balance is regulated by an intricate oxygen-sensing process in the body, the discovery of which earned the 2019 Nobel Prize in Medicine shared by Dana-Farber scientist William G. Kaelin, Jr., … Read more
Medically reviewed by Peter C. Enzinger, MD Barrett’s esophagus is a complication of gastroesophageal reflux disease, or GERD, and can sometimes be a precursor for esophageal cancer. The condition occurs when the tissue lining the esophagus (the tube that carries food from the mouth to the stomach) begins to resemble tissue that lines the intestines … Read more
Consisting of a 2.4-mile swim, a 112-mile bike ride, and a 26.2-mile run, an Ironman Triathlon is not for the faint of heart — and completing it is a feat worth celebrating. After conquering the race, Dan Luers believed he was ready for whatever life had in store. Nothing could have prepared him for a … Read more
The most commonly diagnosed blood cancers are non-Hodgkin lymphoma, chronic lymphocytic leukemia, acute myeloid leukemia, acute lymphoblastic leukemia, and multiple myeloma. Here’s what you need to know about each type of cancer. Non-Hodgkin lymphoma Non-Hodgkin lymphoma (NHL) is a type of cancer that forms in the lymph system, part of the body’s immune system. There … Read more
Medically reviewed by Katherine A. Janeway, MD Cancer affecting the bones may be primary (a cancer that develops within the bone) or metastatic (spreading to bones from elsewhere in the body). Many primary bone tumors are benign (noncancerous), but others are malignant. Treatment options for bone tumors include surgery, chemotherapy, radiation therapy, cryosurgery (freezing cancer … Read more
In early 2019, Jess Skyleson found herself in a situation she never imagined she’d ever be in: telling a group of people what hope means to her. Less than a year ago, as she waded through her own cancer diagnosis, the idea of hope was the last thing Skyleson wanted to discuss. In 2018, she … Read more
Caregivers play a vital role in helping cancer patients face the daily challenges of their diagnosis. While everyone’s needs may vary, caregivers are often asked to assist a patient with their meals. This help comes in many forms, from preparing a single dish to grocery shopping. No matter what you’re asked to do, it’s important … Read more
Earlier this year, a novel drug became the first agent to receive U.S. Food and Drug Administration (FDA) approval for patients with multiple myeloma who have exhausted all types of currently available therapies, including proteasome inhibitors, immunomodulatory drugs and monoclonal antibodies. A clinical trial found that 26.2 percent of such patients responded with significant shrinkage … Read more
Medically reviewed by David M. Weinstock, MD, and Eric Jacobsen, MD By banding together to study the basic biology and vulnerabilities of T-cell lymphoma, scientists at several major cancer research centers have sparked a surge of clinical trials of promising treatments for the disease. The string of new trials, some already open, some expected to … Read more
There was a time when Bradley McGregor, MD, had what many would consider an unusual morning routine for an oncologist. Getting ready for work included putting on nearly 60 pounds of body armor, donning a tactical helmet, and grabbing his assault rifle before heading out the door. His commute took him from an American compound, … Read more
Medically reviewed by Rachael Grace, MD In the mid-1960s, David G. Nathan, MD, president emeritus of Dana-Farber and, at that time, a hematologist at Boston Children’s Hospital, published some of the first reports on a rare, inherited type of anemia caused by the breakdown of red blood cells because of a lack of a key … Read more
It was anything but a routine hospital visit, but Bradley Graham handled his 100th chemotherapy infusion like he has all the rest — with a friendly smile and a steely determination. That’s his makeup. As a principal engineer specializing in submarines and nuclear emergency planning, and a Navy veteran who served more than 20 years … Read more
E-cigarettes have grown in popularity in recent years, especially among teens, whose e-cigarette use now exceeds that of traditional cigarettes. With this increase have come growing concerns about the long- and short-term health effects of vaping. What is vaping? Tan: Vaping refers to the use of e-cigarettes, which heat up a liquid to produce an … Read more
Anthony Guido sums up his life largely in numbers. He worked construction for more than 30 years, has ridden 500,000-plus miles by motorcycle since turning 18, and shares a combined four children and 16 grandchildren with his wife, Shelly. Guido is proud of it all, but what has him most excited these days is marking … Read more
In 1992, when he launched his own Dana-Farber laboratory, William G. Kaelin, Jr, MD, was well-positioned to make potentially landmark discoveries. As a physician, he had an encyclopedic knowledge of human diseases, including rare genetic conditions like von Hippel-Lindau (VHL) disease, which is associated with an elevated risk of benign and malignant tumors, particularly in the kidney. … Read more
If you’ve ever thought about starting a diet, you’re not alone. Studies suggest that more than 45 million Americans will attempt to diet every year. While it’s easy to find a regimen that claims you’ll lose weight and feel better, how do you know it’s safe or even good for you? The amount of misinformation … Read more
This article originally appeared on Discoveries, the blog of Boston Children’s Hospital. No one knew the heartache about to unfold when Savannah and Brett Lillywhite first began thinking about having a family 10 years ago. The Lillywhites Savannah and Brett are both the unlikely carriers of a rare condition called Shwachman-Diamond syndrome — SDS for short — … Read more
Medically reviewed by Catherine J. Wu, MD Within every human cell, a fateful balance prevails. The mitochondria — where nutrients from food are converted into fuel for the cell — serve as a kind of jury box where pro-survival proteins contend with proteins that favor cell death. In the ebb and flow of these proteins, … Read more
Barry Nelson describes his family’s cancer history as “prolific.” Nelson’s grandmother, mother, and two aunts all died from cancer, and it seemed like Nelson might be next. “One morning, I woke up and I had a pain in my neck on my left side. I went to my primary care physician and, ultimately, I found out … Read more