For about 70 years, the standard treatment for patients with advanced prostate cancer was drugs that blocked male hormones feeding the tumor. If that stopped working and the disease progressed, oncologists turned to chemotherapy to kill the cancer cells. This timetable is about to change. Results of a clinical trial led by a Dana-Farber researcher … Read more
Treatments that unleash the body’s own disease-fighting cells against cancer – an approach known as immunotherapy – have been heralded as the “Breakthrough of the Year” by Science magazine.
By Christopher Lathan, MD, MS, MPH When cancer strikes someone who is already facing other hardships – for example, he or she is poor, alone, or has a language barrier – the experience is very different than it might be for someone who has more resources and support. The Cancer Care Equity Program at Dana-Farber, … Read more
Quite a few substances used in traditional medicine in China or other countries have received Food and Drug Administration (FDA) approval as cancer drugs… and their numbers are growing. Some examples are: Arsenic trioxide, made from arsenic sulfide ore, has been used therapeutically for more than 2,400 years. Following promising reports from China, the agent … Read more
Breast cancer is the most common type of cancer in women, but men can also be diagnosed with the disease. How common is breast cancer in men? While male breast cancer is rare, according to the National Cancer Institute about 2,000 men will receive this diagnosis every year, or less than 1% of all new … Read more
Fernando Morales is a student athlete. Last year he was sidelined from the life he knew after he was diagnosed with Ewing sarcoma. Now done with treatment Fernando is back with his teammates, sporting a positive outlook and a new appreciation for life. This is his story. As a soccer player and member of the … Read more
A pill bottle isn’t the only option for relieving stress and discomfort caused by cancer and its treatments. Sometimes you can eat your way to feeling better. Dana-Farber nutrition expert Stacy Kennedy, MPH, RD, suggests some common foods that can pep you up, calm you down, relieve nausea, and potentially fight cancer at the same time.
Aspirin has been around for over 100 years. In the last 50 years, research has shown that regular use of aspirin may prevent heart disease. Now a new study points to aspirin’s effectiveness in preventing and treating cancer. A recent University of Oxford investigation pooled more than 50 studies to show that regular aspirin use … Read more
It’s not always easy to recognize that we live in a golden age. Too often we fail to appreciate the amazing things going on around us because we‘re so caught up in day-to-day activities and pressing demands that we presume that the extraordinary is rather ordinary. So it may be with cancer treatment in 2012. … Read more
If you have received a positive result from a GRAIL Galleri test, which is a multi-cancer early detection (MCED) blood test, you need further testing to determine if you have cancer. If you have a positive GRAIL test, that means the test has found a signal that is associated with cancer and requires investigation. Other … Read more
What is NUT carcinoma? NUT carcinoma, formerly known as NUT-midline carcinoma, is a rare but very aggressive cancer that can develop anywhere in the body but usually starts in the head, neck, and lungs. It’s a squamous cell cancer — meaning it begins in squamous cells, which line hollow organs such as the windpipe and … Read more
Like a mill crumbling into a river, solid tumors constantly shed bits of themselves — including their DNA — into the bloodstream. This free-floating genetic material, known as circulating tumor DNA, or ctDNA, contains a trove of information about the tumor. Advances in technology have made it possible to extract ctDNA from a blood sample, … Read more
On June 7, 2023, New York City had the world’s worst air quality as smoke from Canadian wildfires drifted southward. Images of the city showed orange skies and a barely visible skyline. Air pollution is a leading cause of death worldwide and is also connected to cancer. According to the American Lung Association (ALA), long … Read more
Doctors use traditional radiation therapy to guide a beam of radiation toward a tumor, making every effort to minimize the effects of that radiation on surrounding healthy tissue. But some tumors are hard to treat this way because the tumors don’t stay put. They move as a patient breathes or even as they digest. MRI-guided … Read more
When Bekah Cunningham completed the final mile of the Appalachian Trail in November 2019, it was the culmination of an incredible journey of far more than the nearly 2,200 miles she’d covered over seven months. It was even more incredible considering that three years earlier, the then-29-year-old was told she had lung cancer and only … Read more
Non-small cell lung cancers (NSCLCs) that are most loaded with genetic mutations are most susceptible to immunotherapy drugs known as PD-L1 inhibitors, a new study by Dana-Farber researchers shows. The study, published recently in JAMA Oncology, can help doctors identify patients with the disease who are likely to benefit from the drugs, which foil tumors’ … Read more
Technically speaking, a tyrosine kinase is an enzyme that transfers a compound called a phosphate group from ATP — a molecule that stores energy — to a specific area on cell proteins. It helps transmit the signals that cause cells to grow and divide and to perform specific functions in the body such as burning … Read more
While some racial and ethnic groups have been underrepresented in clinical trials of therapies for lung cancer, breast cancer and other malignancies, researchers speculated that the situation might be different for adult leukemia trials. The unique features of the disease — the speed with which it needs to be treated after diagnosis, the delivery of … Read more
In an era when targeted therapies are often effective against multiple types of cancer, the U.S. Food and Drug Administration’s accelerated approval of a two-drug therapy for solid tumors carrying a specific mutation in the BRAF gene is a prime example of this trend. For patients with glioma brain cancer that harbors the mutation, the … Read more
The connection between a researcher’s biography and area of study is not always obvious. A young scientist may discover an intellectual fascination with immunology, for example, despite not having known anyone with an immunological disorder. For Dana-Farber’s Narjust Duma, MD, however, research is not just a response to her life experiences. It’s a way to … Read more