In 2018, Suzy Pope was diagnosed with an aggressive form of cancer known as glioblastoma. Typically forming in the brain or spinal cord, glioblastomas tend to have a fairly grim prognosis. But two and a half years after her diagnosis, Pope continues to thrive and make the most of every day. Her exceptional response to … Continued
Ependymomas are some of the most difficult-to-treat brain tumors. Mariella Filbin, MD, PhD, a neuro-oncologist at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, is driven by a desire to find new therapies for these pediatric brain tumors. At the core of her work is an effort to uncover the events that shape tumor development. Defining how … Continued
Treatment advances for multiple myeloma continue to bring improved outcomes for patients in different stages of their disease. Recent clinical trial reports show progress in treating two myeloma populations — newly diagnosed, transplant eligible patients, and individuals whose disease has progressed following several lines of therapy. In one trial, the phase 2 GRIFFIN study showed … Continued
The ongoing COVID-19 pandemic has resulted in a uniquely uncertain and stressful way of life for us all. Not knowing what will happen next — in addition to fear for our own health, that of our loved ones, and the disruption to our lives — can lead to distress and depression. This can be particularly … Continued
Liver cancer that develops in people with obesity and Type 2 diabetes is dependent on elevated amounts of a protein that might be targeted for treatment by two existing drugs, say Dana-Farber scientists. The research reported in Cancer Research by Pere Puigserver, PhD, and colleagues pertains specifically to liver cancer in individuals who are obese … Continued
Immunocompromised individuals are potentially at a higher risk for severe illness from the coronavirus, or COVID-19, according to the Centers for Disease Control and Prevention (CDC). We’re here to help — here is some general information about what it means to be immunocompromised, and how you can protect yourself. This information is specific to people … Continued
By Mae Reilly, MS, RD, LDN, senior clinical nutritionist at Dana-Farber Cancer Institute “Does sugar feed cancer?” is one of the most frequently asked questions we receive as oncology dietitians. Researchers continue to investigate the relationship between sugar intake and cancer; meanwhile, there are steps you can take to avoid any potential harm that sugar … Continued
Lymph nodes are key components of the body’s immune system. These small, bean-shaped capsules are located throughout the body and are responsible for filtering lymph fluid and removing harmful substances. They also contain immune cells, which help fight infections by attacking germs and bacteria carried through this fluid. Typically, lymph nodes are soft and undetectable. However, … Continued
In a small percentage of women, a painful breast lump turns out to be cancer.
Lung cancer is divided into two general categories based on its appearance under the microscope: small cell and non-small cell. Non-small cell is the more common type and currently accounts for about 87 percent of lung cancers. Doctors make a distinction between the two types of lung cancers because treatment approaches differ for each. There have been many … Continued
Due to COVID-19, Ava Girolimetti doesn’t know if she will be starting middle school this September in a classroom, on a computer screen, or a combination of both. But thanks to CAR T-cell therapy for acute lymphoblastic leukemia (ALL), she plans to be there cancer-free. The rising sixth grader can make this claim as one … Continued
There are many different treatment options available for breast cancer, including a type of surgery called a lumpectomy. While surgery can be anxiety-inducing, rest assured that lumpectomies are extremely safe and usually take no more than an hour. Here, Anna Weiss, MD, a breast surgeon in the Breast Oncology Program at the Susan F. Smith Center for Women’s Cancers at Dana-Farber/Brigham … Continued
While the vast majority of people diagnosed with cancer do not develop a different malignancy later in life, it’s important for survivors to be aware of factors that can put them at risk. People who have had cancer may in some cases have a higher than average risk of developing a new cancer — that … Continued
Nolan and Natasha might never have met if they hadn’t been diagnosed with bone cancer. Nolan, 13, is a natural athlete who lives in Maine. Natasha, 11, lives in Rhode Island and loves music and theater. As kids go, the two are pretty different — except for their osteosarcoma diagnoses and the surgery they received … Continued
BRCA1 and BRCA2 are cancer-susceptibility genes, meaning that people who inherit pathogenic* mutations in either one have an increased risk of developing certain cancers. Hereditary (or “germline”) mutations in BRCA1 or BRCA2 cause Hereditary Breast and Ovarian Cancer Syndrome. Having a pathogenic mutation in BRCA1 or BRCA2 doesn’t mean you will definitely develop cancer, but … Continued
For many patients with multiple myeloma, a new generation of drugs and drug combinations is producing better outcomes and fewer side effects. In recent months, several novel therapies studied and tested by Dana-Farber scientists have gained approval from the U.S. Food and Drug Administration (FDA) or taken a step toward approval after posting solid results … Continued
As a nurse, Nadege Vilnaigre has devoted her professional life to helping those facing serious medical challenges. Her determination to stay on the job hasn’t waned — even in the face of her own experience with cancer. Vilnaigre is being treated at Dana-Farber for inflammatory breast cancer, which she was diagnosed with in September 2019. … Continued
Two years ago, with a new wife and large extended family on his mind, Jose Dos Anjos told caregivers he would do anything to help himself and others facing the aggressive, life-threatening blood cancer known as mantle cell lymphoma (MCL). Now, thanks in part to this willingness, he and fellow MCL patients have renewed hope … Continued
An immune checkpoint inhibitor is a drug that unleashes an immune system attack on cancer cells. Often made of antibodies, checkpoint inhibitors act on the immune system, therefore such drugs are known as immunotherapies. How do checkpoint inhibitors work? Checkpoint inhibitors seek to overcome one of cancer’s main defenses against an immune system attack. Immune … Continued
Dana-Farber researchers, with colleagues at Columbia University and the National Institutes of Health, have identified a diverse set of antibodies that effectively neutralize the coronavirus responsible for COVID-19, a key step in the development of agents to treat and prevent the disease. As reported in Nature, the antibodies exhibited “exquisite potency” against the virus, thwarting … Continued
