The same way you can predict whether a family is away, getting ready for work, or cooking dinner by observing which lights are on in the house, scientists can gaze into a cell and predict its state based on which genes are on or off. Normal liver cells, for instance, have a predictable and recognizable … Read more
Prostate cancer is the second most common cause of cancer in men worldwide as of 2020, and cases of advanced prostate cancer continue to rise. Early detection of prostate cancer is essential for effective treatment. Dana-Farber physicians recommend having a conversation with a medical professional about screening around the age of 40, or perhaps even … Read more
Investigators who run investigator-initiated trials (IITs) have two essential qualities. One is curiosity, which keeps them alert, aware of discoveries, and able to make connections that lead to new treatment ideas. The second is determination. “The burden of responsibility for what is typically a many-year-long study falls on that one investigator,” says Ursula Matulonis, MD, … Read more
A frequent component of treatment for breast cancer is surgery to remove the cancer. While mastectomy was more common in decades past, experts at Dana-Farber want you to know that science and treatment have advanced. Improved screening, early diagnosis, and advances in medicine are enabling many more patients to have the option of breast-conserving surgery, … Read more
What is NUT carcinoma? NUT carcinoma, formerly known as NUT-midline carcinoma, is a rare but very aggressive cancer that can develop anywhere in the body but usually starts in the head, neck, and lungs. It’s a squamous cell cancer — meaning it begins in squamous cells, which line hollow organs such as the windpipe and … Read more
Laura Orfanedes was worried that she was going to end up with breast cancer. No one in her family had it, and yet she could not shake the feeling. So she took action. She went in for her first mammogram at age 40. In December 2009, at age 43, her annual scan showed an area … Read more
Patti Keenan was a senior in high school before learning that the mysterious disease she was treated for twice as a young girl in the 60s was, in fact, a rare form of cancer. Her parents, not wanting to frighten Patti at a time when pediatric cancer survival rates were much lower, kept their daughter’s … Read more
In the fall of 2019, John Brazeau’s back pain got so bad that it interfered with his ability to engage in the two hobbies he loved most in his retirement on Cape Cod: golfing and clamming. Despite keeping up with physical therapy exercises meant to relieve the pain, it wasn’t diminishing. Then in 2020, Brazeau … Read more
David Trueblood’s long career in journalism was shaped by new technology, including the rise of digital photography and the impact of online media. So, upon learning in early 2023 that he would need a stem cell transplant due to myelodysplastic syndrome (MDS), a rare blood disorder impacting his bone marrow, Trueblood appreciated the role innovation … Read more
Jake Maguire was just three days away from his sixth birthday when he was diagnosed with acute lymphoblastic leukemia (ALL). Encouraged by his father, a gym teacher, the young Maguire was already in love with sports, especially baseball. Now 23 and over a decade out of treatment, that love is still strong, and Maguire is … Read more
There are several types of lung cancer. On a basic level, lung cancers fall into two main subtypes: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Just as each person is unique, every lung cancer is unique. At Dana-Farber’s Lowe Center for Thoracic (Lung) Cancer Treatment Center, oncologists work with a team … Read more
A growing body of research points to a connection between alcohol consumption and elevated cancer risk. Studies from the American Institute for Cancer Research have found that having even less than one drink a day, of any kind of alcohol, increases the risk of several types of cancer, including breast, colorectal, esophageal, liver, stomach, mouth, … Read more
Michelle Karalekas’ time in the Mont Tremblant Ironman Triathlon in Quebec on Aug. 20 — 14 hours, 5 minutes — was not her fastest in the grueling event, but it may have been her most impressive. It was the first time she’d competed since undergoing a stem cell transplant for acute myeloid leukemia (AML) almost … Read more
In the culinary world, cooking oils like olive, avocado, vegetable, and canola, are indispensable. But amid the frying, sautéing, and dressing, whispers of concern have arisen regarding the potential link between cooking oils and cancer. There is ongoing research into the relationship between cooking oils and cancer, as well as the chemical reactions created during … Read more
By Julia Segovia By the time I found out that my mother, Melbey Segovia, had stage III ovarian cancer, she had already had a hysterectomy and started chemotherapy. It was three months after her Feb. 2016 diagnosis. At first I felt a lot of anger around Mom not telling me sooner, but then I understood … Read more
The last thing Alan Rubin imagined he’d be doing after retiring from a successful career in financial services was helping his son run a hot dog cart. Then he was diagnosed with stage III kidney cancer, and found himself in another unexpected locale: Dana-Farber Brigham Cancer Center. Like the decision to join his son’s business … Read more
In 2013, Camille Molloy had just returned from her annual winter trip to Marco Island, in Florida. She and her husband of 57 years, Pete, were carrying their luggage up the stairs, and she tripped. A few weeks later, Molloy was still struggling to walk, so she went in for an X-ray. The image inadvertently … Read more
The trip from Nantucket to Boston, involving a long drive and ferry ride, is an arduous four-hour journey (not counting summer traffic). But when Nantucket resident and retired educator, Claudia Kilvert, was diagnosed with breast cancer, she committed to regularly getting in the car with her husband and 80-pound golden retriever Luna to get treatment … Read more
Treatments used for many forms of cancer, as well as certain rare types of cancer that directly affect the ear(s), can affect your hearing. It’s important to understand the possibilities and know what to look for because, in some cases, early action can help. If you are affected by hearing loss, there are also resources … Read more
Colon and rectal cancer combined are the fourth most commonly diagnosed cancers. Eighty percent of patients are diagnosed at a stage of disease when treatment is given with curative-intent. However, treatment can have both short- and long-term side effects that may impact quality of life. To address these concerns, investigators at Dana-Farber have led clinical … Read more