Cancer research
How Do PARP Inhibitors Work In Cancer?

PARPs (or Poly (ADP-ribose) polymerases)  are proteins that play an important role in the life of a cell. When a strand of the DNA double helix is broken or damaged, PARPs  act as a repair crew to help fix the damaged site, allowing the cell to live. For healthy cells […]

July 21, 2016
0
Cancer research
What Are Precursor Blood Conditions and How Are They Treated?

Precursor conditions are early phases of blood diseases that may develop into cancers such as lymphoma, leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. Most people do not experience symptoms, and since doctors rarely screen for precursor conditions, they are often diagnosed after routine blood tests. “Many diagnoses are purely incidental,” says […]

July 15, 2016
0
Cancer research
Fighting Women’s Cancers from Within

Traditionally, the war on cancer has been waged from the outside in, with therapies such as surgery, radiation, and drugs entering the body from external sources. For more than 100 years, however, a notion has persisted that the most formidable tool against cancer may come from within: the immune system. […]

June 27, 2016
0
Cancer research , Care for adults
Individualized Clinical Trial Gives Patient with Rare Cancer Time to Celebrate

Kerri Antonuccio marked her 40th birthday this spring with a fresh lease on life. For the first time since 2012, she didn’t feel too sick from cancer treatment to enjoy her big day. She was also able to travel to Mexico and serve as matron of honor at her sister’s […]

June 20, 2016
2
Cancer research
Can Vitamin D Reduce Cancer Risk?

Scientific evidence that vitamin D can help lower the risk of cancer development, as well as the risk of metastasis or recurrence, has been mixed. But several new studies point toward such a connection for certain cancers. Numerous population-tracking studies over the years have shown that higher intake or blood […]

June 17, 2016
1
Cancer research
ASCO 2016 Update: Immunotherapy and Melanoma

As one of the hottest topics in cancer research today, immunotherapy took center stage at the 2016 American Society of Clinical Oncology meeting in Chicago. Harold J. Burstein, MD, PhD, a breast oncologist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber Cancer Institute, recently sat down with […]

June 15, 2016
0
Cancer research
How Can Bioinformatics Help Advance Precision Cancer Care?

Scattered amongst the letters of genetic code in a tumor cell are telltale mutations and DNA alterations that spur its malignant activity. But there are billions of letters of code and each patient’s cancer is different, with its own particular genetic changes. These changes may dictate how it behaves, how […]

May 27, 2016
0
Cancer research , Care for adults
From Cancer Researcher to Patient and Back

By Katherine Walsh When faced with something as scary and life-changing as a cancer diagnosis, the way we see the world drastically changes. My story is a literal shift – from cancer researcher to leukemia patient, and a very sick one at that. My world came to a screeching halt […]

May 23, 2016
0
Cancer research
Can Stress Affect Cancer?

Stress is generally defined as a condition in which the body or mind is placed under strain or tension. Stress is a normal part of life. In fact, studies show it to be a necessary part of life, prompting us to adapt and become more resilient. But if it becomes […]

May 19, 2016
2
Cancer research , Care for adults
A Behind the Scenes Look at the People Helping to Usher in New Cancer Therapies: A Nurse’s Story

This post originally appeared on HuffPost Impact. By Joan Lucca, RN, MSN Nearly four decades ago, I became a nurse and dedicated my life’s work to the care and comfort of patients. The ‘70s was a decade of change and opportunity as doors began to open for women in emerging […]

May 17, 2016
0
Cancer research
Team Care and Positive Attitude Help Rectal Cancer Patient Through Treatment

Back when D.N. Chadha, MA, was a pharmaceutical executive meeting with Jeffrey Meyerhardt, MD, MPH, in 2002, he never imagined he’d see the physician years later – this time for rectal cancer treatment. “The name rang a bell, and as soon as I saw him, I knew,” says Chadha, 74, […]

May 16, 2016
0
Cancer research
What Is a Liquid Biopsy?

A traditional biopsy is a test in which a piece of tissue is removed from a patient for analysis in a laboratory. A pathologist examines the tissue under a microscope, noting the shape, structure, and internal activity of the cells to determine whether the cells are cancerous and, if so, […]

April 20, 2016
0
Cancer research
How Scientists Aim to Expand Immunotherapy Options for Cancer Patients

This post also appeared on the NERD (Novartis Explores Research & Development) blog. By Eric Bender Fighting cancer with immunotherapy has revolutionized treatment for some patients. Emphasize “some.” For most patients, drugs targeting the immune system to attack their tumors aren’t an option. This could change in the near future. […]

April 14, 2016
0
Cancer research , Care for adults
FDA Approval of Defibrotide Brightens Outlook for Stem Cell Transplant Patients

Patients and Dana-Farber researchers alike welcomed this week’s Food and Drug Administration (FDA) approval of a new drug for a potentially fatal side effect of stem cell transplants. The approval means patients can receive the drug, defibrotide, as standard therapy for hepatic veno-occlusive disease (VOD) of the liver, a dangerous […]

March 31, 2016
0
Cancer research
Can We Treat Colorectal Cancer With Immunotherapy?

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research (AACR). It is posted here with minor edits. March is Colorectal Cancer Awareness Month. About 134,490 people are estimated to be diagnosed with and about 49,190 are expected to die from colorectal […]

March 21, 2016
0
Cancer research , Care for adults
How Precision Cancer Care Saved a Life

Ronaldo de Oliveira was close to death. The 33-year-old father of two young children had been diagnosed with myeloid sarcoma, a rare form of leukemia that worsened despite treatment with six different chemotherapy regimens. His wife pleaded with his oncologist, Richard Stone, MD, director of the Adult Leukemia Program at […]

March 18, 2016
0
Cancer research , Health and wellness
How Does Alcohol Cause Cancer?

This blog post was originally published on the Cancer Research UK science blog. It is reposted here with minor edits.   In a cabinet in London’s British Museum nestles a 5,300 year-old wedged-shaped tablet called a cuneiform. On its surface is scrawled one of the earliest forms of written language […]

March 3, 2016
0
Cancer research
What Makes Cancer Cells Different from Normal Cells?

Although they may seem like foreign invaders, cancer cells develop out of normal body cells and tissues. Over a period of years, damage to the DNA of healthy cells disrupts their orderly growth, leading to the formation of malignant tumors. Cancer cells may contain thousands of mutations – alterations in […]

March 2, 2016
0
Cancer research
The Cell that Caused Melanoma: Cancer’s Surprise Origins, Caught in Action

This post originally appeared on Vector, Boston Children’s Hospital’s science and clinical innovation blog. It’s long been a mystery why some of our cells can have mutations associated with cancer, yet are not truly cancerous. Now researchers have, for the first time, watched a cancer spread from a single cell […]

February 17, 2016
0
Cancer research
The Latest Research in Multiple Myeloma, Leukemia and Other Blood Cancers

The last two years have been very exciting for blood cancer research; many new targeted therapies and immunotherapies are improving treatment outcomes for patients with lymphoma, leukemia and multiple myeloma. “We’re starting to see a lot of hematologic malignancies benefit from immunotherapy,” says Irene Ghobrial, MD. “The excitement is there […]

February 11, 2016
0
Cancer research , Care for adults
What Are the Side Effects of Immunotherapy?

New drugs that stimulate the patient’s immune system to attack tumors have achieved some dramatic and long-lasting benefits in several forms of cancer. A few drugs are already approved for wide use and many more are in the research pipeline. Because these immunotherapy agents work differently than chemotherapy, they can […]

February 10, 2016
4
Cancer research , Care for children
In Precision Medicine, Pioneering Young Patient Teaches Veteran Doctor

Allison Schablein seems an unlikely candidate to teach medicine to Mark Kieran. She’s an 8–year-old New Hampshire second grader who loves basketball, hip hop, acrobatic dancing and jewelry. He’s a pediatric neuro-oncologist with a PhD in molecular biology, not to mention decades of clinical and research experience. But teach Kieran, […]

January 28, 2016
0
Cancer research
What A Cancer Cure ‘Moon Shot’ Might Look Like

This post originally appeared on WBUR’s CommonHealth blog. By Barrett Rollins, MD, PhD President Obama’s call for a new national effort against cancer – a “moon shot” – comes at a most opportune time. Cancer research has advanced significantly and now genomic analysis of individuals’ tumors can reveal the specific […]

January 14, 2016
2
Cancer research , Care for adults , Health and wellness
When Should I Begin Regular Mammograms? [Infographic]

For women weighing when to start having regular mammograms for early detection of breast cancer, the answer isn’t always clear. The American Cancer Society (ACS) recommendations, which were updated in October 2015, specify that women aged 45-54 who are at average risk should undergo yearly mammograms, and every two years […]

January 12, 2016
0
Cancer research , Care for adults
The Latest in Prostate Cancer Research and Treatment

Prostate cancer is the most common cancer affecting men in the United States, after skin cancer. Yet, “most men die with prostate cancer, not of prostate cancer,” says Mark Pomerantz, MD, a medical oncologist in Dana-Farber’s Lank Center for Genitourinary Oncology, who recently shared the latest in prostate cancer research […]

December 23, 2015
2
Cancer research
What Is CTLA-4 and How Does it Work in Treating Metastatic Melanoma?

Since the early 2000s, when Dana-Farber scientists discovered that many cancer cells carry “checkpoint” proteins that ward off an immune system attack on tumors, a great deal of research has focused on the development and testing of agents capable of blocking those proteins. In many patients, such agents have sent […]

December 15, 2015
0
Cancer research , Care for adults
Remission of Jimmy Carter’s Melanoma Shows Potential of Immunotherapy for Cancer

Former President Jimmy Carter’s announcement earlier this week that he is free of the melanoma that had spread to his liver and brain may be the highest-profile example yet of the promise of a new form of cancer treatment that unleashes an immune system attack on the disease. Carter, 91, […]

December 11, 2015
1
Cancer research
A New Class of Cancer Drug Moves Closer to Potential FDA Approval in Leukemia

Updated April 13, 2015 Venetoclax, a new type of cancer drug known as a Bcl-2 inhibitor, is showing great promise against a poor-prognosis form of chronic lymphocytic leukemia (CLL), and could work in other cancers as well. Venetoclax, formerly known as ABT-199, attacks the protein molecule, Bcl-2, that allows cancer […]

December 6, 2015
0
Cancer research
Immunotherapy and Lung Cancer: Exploring the Latest Research

The year 2015 marked a milestone in the treatment of lung cancer, with two new immunotherapy drugs approved for patients with advanced disease, bringing a new approach to this hard-to-treat cancer. Several other immunotherapy agents are also moving forward in clinical trials. In the past few years, scientists have found […]

November 18, 2015
1
Cancer research , Care for adults
FDA Approves New Drug for Some Patients with Non-Small Cell Lung Cancer

The FDA announced today it has approved a new pill to treat certain patients with advanced non-small cell lung cancer (NSCLC). The oral medication, Tagrisso (osimetinib), has been approved for NSCLC patients whose tumors have a specific epidermal growth factor receptor (EGFR) mutation (T790M) and whose disease has worsened after […]

November 13, 2015
0
Cancer research
Hot Topics in Immunotherapy and Targeted Therapy

This blog post is an excerpt from a Q&A posted on the Cancer Research Catalyst blog, the official blog of the American Association for Cancer Research. The interview was done with Dana-Farber’s Levi Garraway, MD, PhD, in advance of the International Conference on Molecular Targets and Cancer Therapeutics.   What […]

November 12, 2015
0
Cancer research , Care for adults
The Latest in Genetics and Women’s Cancers

Knowledge of genetics and women’s cancers has come a long way in the 20 years since the BRCA1/2 genes were discovered. Scientists are able to identify more genes that can increase risk, leading to better prevention and improved treatment. “One of the most exciting developments is the knowledge that patients […]

October 29, 2015
0
Cancer research , Health and wellness
The Link Between Processed Meat and Cancer: What You Need to Know [Infographic]

Eating processed meat products, such as hot dogs and bacon, can increase a person’s risk for colorectal cancer, according to research from an international cancer agency. The International Agency for Research on Cancer (IARC), the cancer agency of the World Health Organization (WHO), said today that processed meat is “carcinogenic […]

October 27, 2015
6
Cancer research
FDA Approves Immunotherapy Drug Combination for Melanoma

This blog post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. By Karen Honey, PhD Last week, new ground was broken in the field of cancer immunotherapy when the U.S. Food and Drug Administration (FDA) approved the first cancer treatment to combine […]

October 6, 2015
0
Cancer research , Care for adults
What Is CA-125?

CA-125, the abbreviated name for cancer antigen 125, is a protein that’s often elevated in ovarian cancer as well as other types of cancers, such as those of the lung and breast. It’s also elevated when disease or inflammation arises in the pleura – the tissue that enfolds the lungs […]

September 28, 2015
0
Cancer research , Care for adults
Can Two Ovarian Cancer Drugs Succeed Where Others Have Failed?

When Donna Gregory’s ovarian cancer came back for the third time, she began looking for alternatives to chemotherapy. She’d been diagnosed with stage III ovarian cancer in 2003, at age 58. After having surgery to remove her tumors, she tried platinum-based chemotherapy, but her cancer did not respond. Several more […]

September 21, 2015
2
Cancer research , General interest
Federally Funded Research Can Power Progress Against Cancer

This post originally appeared on the AACR Cancer Research Catalyst Blog. This week, the American Association for Cancer Research (AACR) released the results of a national survey on American voters’ opinions about cancer and cancer research funding in conjunction with its fifth annual Cancer Progress Report. The report highlights how […]

September 18, 2015
0
Cancer research
What Is a Checkpoint Inhibitor? Immune Checkpoint Inhibitor Definition

Immune checkpoint inhibitors are drugs – often made of antibodies – that unleash an immune system attack on cancer cells. They’ve scored some impressive successes in recent years, particularly in some patients with metastatic melanoma or Hodgkin lymphoma, and are showing promise in clinical trials involving patients with other types […]

September 9, 2015
0
Cancer research
Finding the Best Targets for Precision Cancer Treatment

The inner world of a cancerous tumor is a place of intense rivalry, subversion, and aggression. Multiple subgroups of malignant cells – each with its own pattern of molecular features – vie with one another for nutrients, access to the blood supply, and room to grow and spread. This diversity, […]

September 4, 2015
0
Cancer research , Care for children
Childhood Cancer and the Promise of Gene Therapy

At its most basic level, gene therapy is a powerful technique for correcting mistakes (called mutations) in DNA of human cells. Lately, the therapy has been gaining traction as a potentially life-saving treatment for children with an array of inherited rare blood and immune disorders, as well as certain cancers. […]

August 21, 2015
0
Cancer research , Care for children
Progress in the Treatment of Childhood Leukemia

Although treatments for childhood cancer patients are improving, cancer remains the leading cause of death by disease in children. Doctors and researchers are also focused on decreasing the toxicity of these treatments, which can have side effects years after a child finishes treatment. “The war against childhood cancer is hardly […]

August 13, 2015
0
Cancer research , Care for adults
I Have Metastatic Breast Cancer: What’s My Prognosis?

By Rachel A. Freedman, MD, MPH Metastatic breast cancer generally means that the cancer has spread beyond the breast and nearby lymph nodes under the arm. For approximately 10 percent of women with breast cancer, the disease has metastasized when they are first diagnosed, but metastatic disease can also occur […]

August 12, 2015
1
Cancer research , Care for adults
Do All BRCA Mutations Come with the Same Cancer Risk?

Women born with mutations in the genes BRCA1 or BRCA2 have an increased risk of developing breast and ovarian cancer, but the degree of increase depends on a variety of factors. Not all mutations within these genes raise the risk equally. A study published earlier this year tracked breast and ovarian […]

July 29, 2015
2
Cancer research , Health and wellness
Why I Ride: Dr. Christopher Sweeney

Since 1980, more than 88,000 cyclists have taken to Massachusetts’ roads for the Pan-Mass Challenge (PMC) to raise funds for cancer research and patient care at Dana-Farber. Among the riders are many patients, their family members, and their doctors. Christopher Sweeney, MBBS, medical oncologist in Dana-Farber’s Lank Center for Genitourinary […]

July 27, 2015
0
Cancer research
Solving Puzzles with Cigall Kadoch

Growing up in the San Francisco area, Cigall Kadoch, PhD, had a passion for puzzles. The daughter of a Moroccan-born, Israeli-raised father and a mother from Michigan who together developed an interior design business, Kadoch excelled in school and pretty much everything else. Above all, she loved to solve brain-teasers. […]

July 23, 2015
1
Cancer research , Care for adults
Approval of Targeted Lung Cancer Drug Iressa Culminates Long Research Trail

The Food and Drug Administration’s approval of the drug Iressa® for a form of metastatic lung cancer represents a return to prominence for the compound that launched the era of targeted therapy in lung cancer – even if that wasn’t clear at the time of its original clinical trial in patients. […]

July 16, 2015
1
Cancer research , Care for children
What’s New in Pediatric Brain Tumor Treatment?

As one of the most difficult cancers to treat, childhood brain tumors are the leading cause of cancer-related deaths in children under age 10. However, researchers are making more progress than ever before. “Over the last 10 years there has been a lot of excitement about new treatments for pediatric […]

July 2, 2015
3
Cancer research
What Is Cancer Immunotherapy?

Immunotherapy is a treatment that uses a patient’s immune system to fight diseases like cancer. This new area of treatment is one of the most promising areas of cancer research today. There are several strategies used in immunotherapy; some simply give the immune system a boost in order to have […]

June 25, 2015
4
Cancer research
Know Your Surroundings: How Cancer Treatments Can Keep Cells From Supporting Tumors

By Eric Bender Multiple myeloma is a poster child for recent advances in treatment: In the past decade, the U.S. Food and Drug Administration (FDA) approved no fewer than nine treatments for the blood cancer, and several more drug approvals appear to be near. Not coincidentally, multiple myeloma is also […]

June 19, 2015
2
Cancer research , Care for adults
Can Women Get More Than One Lumpectomy?

For many women with localized breast cancer, a lumpectomy followed by breast radiation therapy may be the most effective treatment, with survival rates equal to a mastectomy. But if the cancer comes back, can women have additional lumpectomies? Women should not have a second lumpectomy in the same breast if […]

June 15, 2015
1
Cancer research
Immunotherapy, Targeted Drugs, Brain Cancer Research Among Highlights at Cancer Meeting

Eagerly awaited new data from trials of immunotherapy drugs, vaccines to treat brain tumors, and improved treatments for blood cancers sparked waves of optimism at the year’s biggest cancer meeting. The 2015 annual meeting of the American Society of Clinical Oncology (ASCO) drew about 30,000 cancer specialists to Chicago May […]

June 5, 2015
0
Cancer research
How Does the Body’s Immune System Fight Cancer? (Immunotherapy)

Immunology is one of the most promising areas of cancer treatment today. Immunotherapy drugs, which use the patient’s own immune system to fight cancer cells, have been effective in treating several forms of the disease, including melanoma, prostate cancer, Hodgkin lymphoma, and certain types of brain tumors. The immune system […]

June 1, 2015
2
Cancer research , General interest
Explaining the Complexities of Cancer

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research (AACR).  Burgeoning understanding of the biology of cancer has led to advances in cancer prevention, detection, diagnosis, and treatment. These advances mean that a person diagnosed with cancer in the United States […]

May 28, 2015
0
Cancer research
How a Cure for Hodgkin Lymphoma Changed the Course of Cancer Treatment

To mark its 50th anniversary, the American Society of Clinical Oncology (ASCO) invited physicians, patients, and the public to name the most important advances in clinical cancer research in the past half century. From more than 2,000 responses, the top choice was a cure for advanced Hodgkin lymphoma developed by […]

May 25, 2015
1
Cancer research
New Research Brings Better Understanding of Brain Tumors, Treatment Advances

Brain cancer takes a variety of forms – and research to better understand and treat it is progressing on a variety of fronts. One area of focus is the tumor microenvironment the skein of tissues and blood vessels that feed and support a tumor. Researchers are exploring how newly formed […]

May 15, 2015
0
Cancer research
What is the Science of PD-1 and Immunotherapy?

This is a story about the velocity of an idea – a discovery whose potential to improve cancer treatment practically leapt from the test tube. The groundwork was laid in the 1990s, when scientists learned that human cells carry certain proteins on their surface that enable them to escape attack […]

May 13, 2015
0
Cancer research
Patient Turned Researcher Helps Advance Understanding of Brain Tumors

This post originally appeared on HealthHub, a blog from Brigham and Women’s Hospital. Interested in seeing images of his brain, Steven Keating, currently a graduate student at the MIT Media Lab, volunteered for a research study while attending school in Canada in 2007. When researchers returned his brain scans, they […]

May 7, 2015
0
Cancer research , Care for adults
New Study: Chemo Before Surgery Avoids Need for Mastectomy for Many with Triple-Negative Breast Cancer

Chemotherapy before surgery shrank triple-negative breast tumors in women in a clinical trial to the point where half of those who had not been eligible for breast-conserving surgery became eligible for it, according to investigators at Dana-Farber and Brigham and Women’s Hospital. The findings were reported at the American Surgical […]

May 6, 2015
0
Cancer research
From Foe to Friend: Viruses Show New Promise as Cancer Treatment

Updated Oct. 28, 2015 Almost as long as scientists have known of the existence of viruses, they’ve dreamed of using the tiny pathogens as a weapon against cancer. Now, as a result of advances in genetic engineering and insights into the workings of the immune system, science is giving substance […]

May 1, 2015
0
Cancer research , Care for adults
The Latest in Precision Medicine and Lung Cancer

Even before President Barack Obama declared it a national initiative, precision medicine has helped bring more effective treatment to patients with many types of cancer. One disease that has benefited from these treatments is lung cancer, where targeted therapies have significantly improved outcomes for patients. “When we find we have […]

April 30, 2015
0
Cancer research , Care for adults
Promising Research Developments Stir Hopes for Melanoma, Lung, Breast and Ovarian Cancer

The growing excitement about the potential of immunotherapy treatments for cancer continued at the 2015 meeting of the American Association for Cancer Research (AACR), one of the largest cancer research meetings of the year. Several Dana-Farber investigators presented encouraging results of immunotherapy for melanoma, lung cancer, and breast cancer. F. […]

April 24, 2015
0
Cancer research , Health and wellness
What Is a Cancer Vaccine?

Cancer vaccines are medicines that spur the immune system’s natural defenses against cancer. They belong to a class of substances known as biological response modifiers, which strengthen or stimulate a basic bodily process – in this case, the immune system’s ability to detect and attack cancer cells. There are two […]

April 13, 2015
2
Cancer research , Care for adults
What Is It Like to Enroll in a Clinical Trial?

When Elizabeth Cahn was presented with her treatment options for triple-negative breast cancer, the decision was about more than just getting healthy; it was about “paying it forward.” “I know there are many people who participated in clinical trials before I came along and it was because of their participation […]

March 31, 2015
1
Cancer research , General interest
Chronicling Cancer Research in Books and Film

In two recent books and the Ken Burns TV documentary, “Cancer: The Emperor of All Maladies”, prominent researchers explain eloquently why cancer is such a stubborn problem and detail how the latest treatment strategies are gaining ground – if slowly. “There have been so many wonderful changes,” says David G. […]

March 30, 2015
0
Cancer research , Care for adults
Five Common Myths About Clinical Trials

Better cancer treatments depend on clinical trials of new drugs and other therapies, but in the United States, only 3 percent of cancer patients participate in these investigations of new therapies. Patients often hesitate to participate because they don’t understand the process or have misconceptions about what it means for […]

March 9, 2015
2
Cancer research
Discovering New Ways to Approach the Treatment of Rare Brain Tumors

Until a few years ago, there were only a handful of known survivors of atypical teratoid rhabdoid tumor (AT/RT), a rare cancer that affects the brain and central nervous system. When researchers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center studied how these few survivors were treated, they found three […]

February 9, 2015
0
Cancer research , Care for adults
Collaborative Effort Helps Develop More Effective Treatment for Brain Tumors

The information used in diagnosing a brain tumor takes many forms. At Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC), patients’ brain tumor tissue undergoes a broad range of diagnostic tests: not only standard pathology exams in which tumor cells are viewed under a microscope, but also next-generation scans for mutated genes […]

February 4, 2015
0
Cancer research
Why the President’s Precision Medicine Initiative Is Good for Cancer Research

A boost in funding for research on genetic causes of cancer and “tailored” cancer treatments will be a major focus of the new Precision Medicine Initiative. President Barack Obama is requesting an increase of $215 million in the 2016 budget, to launch the effort “to bring us closer to curing […]

January 31, 2015
0
Cancer research , Care for adults
The Latest in Cervical Cancer Treatment, Research and Prevention

Although cervical cancer is relatively rare in the United States, approximately 11,000-12,000 women in the U.S. are diagnosed with the disease each year. Globally, that number grows to more than 500,000 diagnoses each year, making it the fourth most common women’s cancer worldwide. As January marks Cervical Cancer Awareness Month, […]

January 30, 2015
2
Cancer research
What to Expect for Cancer Prevention and Therapies in 2015

This post was originally published on Cancer Research Catalyst, the official blog of the American Association for Cancer Research (AACR).  Since the beginning of the “war on cancer” in the 1970s, we have made consistent progress against cancer aided by paradigm-shifting technological advances. Last year, we witnessed significant developments being made on […]

January 29, 2015
3
Cancer research
Precision Medicine and the Future of Cancer Treatment

Precision medicine is rapidly changing the way cancer is studied and treated today. With new information about genetic and molecular characteristics in tumors, doctors are finding more effective and less toxic ways to fight the disease. “Precision medicine is seeing the monster of cancer clearly for the first time in […]

January 28, 2015
2
Cancer research
A Teen’s Journey: Developing a Diagnostic Test for Pancreatic Cancer

This post was originally written and published on Vector, Boston Children’s Hospital’s science and clinical innovation blog.  At age 13, Jack Andraka lost a family friend to pancreatic cancer. At age 15, he developed a diagnostic test for pancreatic cancer that early findings suggest is highly accurate. In this session from Boston […]

January 21, 2015
1
Cancer research
New Immunotherapy Vaccines Show Promise in Treating Brain Tumors

Researchers in Dana-Farber’s Center for Neuro-Oncology are now launching attacks on glioblastomas from a new angle – by turning the patient’s immune system against the cancer cells. Where targeted chemotherapy uses drugs to disable proteins that cancer cells need to grow, immunotherapy drugs stimulate the patient’s immune system to recognize and […]

January 19, 2015
0
Cancer research , Care for adults
Immunotherapy, Ovarian Cancer Treatment Top List of 2014 Cancer Developments

Immunotherapy, treatments for ovarian cancer, and investigating game-changing drug therapies topped the list of the most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014. Here are some highlights from the last year in research: Hodgkin lymphoma Some of the most dramatic evidence of potential of immunotherapies […]

December 31, 2014
0
Cancer research
The Latest Research and Treatment for Blood Cancers and Disorders

In the treatment of blood cancers and disorders, doctors and researchers are focusing their sights on the immune system and how to bolster its ability to fight off diseases like leukemia, lymphoma and multiple myeloma. “Understanding how you control the immune system is a big theme in treatment for these […]

December 26, 2014
0
Cancer research
Listen: Dr. Sidney Farber Discusses Cancer Research in 1951 Radio Broadcast

In the 1940s, children diagnosed with leukemia had a grim prognosis; there was essentially nothing doctors could offer to treat the young patients, other than cortisone therapy to help with side effects of the disease. But in 1948, Dana-Farber founder Sidney Farber, MD, believed a drug that blocked folic acid would shut down […]

December 4, 2014
0
Cancer research
Latest Research Shows Progress in Fight Against Lung Cancer

Lung cancer, which causes more deaths worldwide than any other malignancy, is revealing its vulnerabilities under a sustained assault from science. Many of the most recent advances against the disease have a long pedigree at Dana-Farber. It was 10 years ago, in fact, that Dana-Farber scientists and elsewhere showed non-small […]

November 14, 2014
0
Cancer research
20 Years After BRCA: What We’ve Learned About Genetics and Breast Cancer

Twenty years ago, scientists announced the discovery of BRCA1, which arguably has become the best-known cancer susceptibility gene in the world. When inherited in a mutated form, the gene sharply increases a woman’s chances of developing breast or ovarian cancer, often at an early age. The discovery has changed the […]

October 31, 2014
0
Cancer research
Keytruda: New Immunotherapy Drug for Melanoma Wins FDA Approval

The Food and Drug Administration has approved a new type of  immunotherapy drug that will provide a much-needed option for patients with advanced or inoperable melanoma who no longer respond to other drugs – including the immunotherapy agent ipilimumab (Yervoy). The drug, pembrolizumab or MK-3745, will be marketed under the name  Keytruda. Based on […]

September 5, 2014
4
Cancer research , Care for adults
Understanding the New Treatment Guidelines for HER2-Negative Breast Cancer

A new national guideline for the treatment of women with a type of advanced breast cancer known as HER2-negative disease balances state-of-the-art evidence with a need to tailor therapy to each patient’s circumstances and preferences. The guideline, developed by a panel of experts convened by the American Society of Clinical […]

September 3, 2014
0

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