Cancer research , Endometrial (Uterine) cancer
Human Touch Surgeries, New Therapies Brighten the Picture in Endometrial Cancer

Although she had been fully prepped on what to expect, Barbara Losordo was a bit surprised at the ease and speed of her recovery from surgery for endometrial cancer. Discharged from the hospital the same day she had undergone the procedure, she needed no pain medication afterward. Within a week, she […]

October 18, 2017
1
Cancer research , Melanoma , Skin cancers (non-melanoma)
New Tanning Drug Could Protect Skin From the Sun

Scientists may have figured out a way to let people tan safely – without involving the sun. In an effort to further develop preventative measures for skin cancers like melanoma, researchers from Dana-Farber and other health care organizations have developed a potential topical cream that stimulates skin cells to produce […]

July 10, 2017
3
Cancer research , Immunotherapy
What’s New in Treatment of Adult Histiocytic Disorders?

While blood cancers known as adult histiocytic disorders are very rare and many patients do well with today’s treatments, researchers are working to improve outcomes with therapies targeted to newly discovered mutations – and they are about to begin testing immunotherapies, too. Histiocytic disorders involved overproduction of immune white cells, […]

June 29, 2017
0
Cancer research , Immunotherapy
In Check: Attacking Cancer from Many Fronts

As a pediatric dentist, Jay Schwab had a clear-cut enemy: dental disease in children and adolescents, and the apprehensions they faced in the dental environment. Cavities could neither hide from his drill nor fool his X-ray machine, and plaque could easily be scraped away. Generations of patients went away smiling […]

June 27, 2017
0
Cancer research , CAR T-cell therapy , Immunotherapy , Research
Catch Me if You Can: Finding Cancer Cells that Hide in Plain Sight

In the high-stakes contest of hide-and-seek between cancer cells and the human immune system, the advantage doesn’t always lie with the body’s defenders. A new approach to treatment, known as CAR T-cell therapy, may shift that balance of power. Cancer cells conceal themselves from the immune system not by barricading […]

June 21, 2017
0
Cancer research , Research
Meet the Researcher: Bruce Spiegelman

Cancer patients often lose weight during treatment, which can limit their ability to withstand treatment and their quality of life. How can we fix this – and what role does energy metabolism play in cancer, and health overall? Those are the questions researcher Bruce Spiegelman, PhD, and his team at […]

June 19, 2017
0
Cancer research , Care for children
An Unclassified Tumor — with a Precisely Targeted Therapy

Early last year, at his home in San Juan, Puerto Rico, Jesus Apolinaris Cruz’s leg hurt so much he could barely sleep. “All day, it was constant pain,” the 13-year-old recalls. His parents took him to two local pediatricians, who examined him, drew blood, and tested his platelets. No diagnosis. […]

June 6, 2017
0
Cancer research , CAR T-cell therapy , General interest
CAR T-Cell Therapy: How Does It Work?

CAR T-cell therapy is a kind of cellular therapy, which uses a patient’s own immune system cells to rally an attack on cancer. They’re made by removing a specific set of cells from the blood, modifying them in a lab to intensify the immune system’s natural response to cancer, and […]

June 2, 2017
2
Cancer research , Podcasts
Cancer Mythbusters Episode #5: Cancer Clinical Trials

Clinical trials are scientific studies in which new treatments – drugs, diagnostic procedures, and other therapies – are tested to determine if they are safe and effective for patients. Nearly all cancer drugs in use today were tested and made available to patients through clinical trials, making them a crucial component of […]

June 1, 2017
0
Bladder cancer , Cancer research , Immunotherapy
How Is Immunotherapy Used to Treat Bladder Cancer?

Although immunotherapy seems like a recent phenomenon, physicians have been using the strategy to treat bladder cancer since 1990, when the BCG vaccine, made from a live but weakened tuberculosis bacilli, was approved for early stage cancer that hasn’t invaded the bladder’s muscular wall. Today, BCG is still the recommended […]

May 30, 2017
2
Cancer Genetics , Cancer research , Colon Cancer , Endometrial (Uterine) cancer , Ovarian cancer
New Online Tool Guides Genetic Testing for Lynch Syndrome

A new online assessment tool developed at Dana-Farber can help rapidly identify people who should undergo genetic testing for Lynch syndrome, an inherited disorder that greatly increases the lifetime risk of colorectal, endometrial, ovarian, stomach, and other cancers. An estimated 1 in 279 individuals – nearly a million people in […]

May 25, 2017
0
Cancer research , General interest , Immunotherapy
The Progress of Cancer Immunotherapy: The Tip of the Iceberg

If the human immune system was a powerful racing car, you could say that scientists in the past few years have gained unprecedented control over how to make it accelerate, and what causes it to slow or stop. This knowledge has spawned new immunotherapy drugs that are delivering dramatic benefits […]

May 9, 2017
2
Cancer research , Treatments and Procedures
Can a Tumor Biopsy or Surgery Cause Cancer to Spread?

There’s little reason to worry that a biopsy or other surgical procedure will allow cancer cells to escape and spread within the body, specialists say. “A common patient concern is that biopsies may cause microscopic cells from cancers to metastasize to other parts of the body,” says Thanh Barbie, MD, […]

May 4, 2017
0
Blood disorders, childhood , Cancer research , Patient Stories, Pediatric
How Pediatric and Canine Cancer Similarities Can Help Both Children and Pets

In March 2016, Ollie the pug, a therapy dog at Boston Children’s Hospital, paid a bedside visit to 7-year-old Carter Mock. Both dog and boy lost limbs to osteosarcoma, a cancer of the bone. Ollie’s left front leg was amputated at the shoulder. After removing the tumor in Carter’s left […]

May 2, 2017
0
Cancer research , Care for adults , Gastrointestinal Cancer , Pancreatic cancer , Precision Cancer Medicine
Attacking A Weak Point in Pancreatic Cancer’s Defense

In the fall of 2015, at the age of 44 – young for a person to be diagnosed with pancreatic cancer – Doron Broman was stunned to learn he had a large tumor on his pancreas that had metastasized to the liver. Facing only months to live, Broman would find […]

April 26, 2017
0
Blood Cancer , Cancer research , Leukemias , Lymphomas , Multiple Myeloma , Research , Stem cell/Bone marrow transplant
The Latest Advances Against Hematologic Cancers

Treatment of blood-related, or hematologic, cancers is seizing on insights into the basic genetic wiring of cancer cells and the body’s system for finding and attacking those cells. Research presentations at the annual American Society of Hematology (ASH) meeting in December gave evidence of how broad, and rapid, the progress […]

April 21, 2017
2
Cancer research , Care for adults , Head and Neck Cancer , Immunotherapy
What’s New in Immunotherapy for Head and Neck Cancer?

For patients with advanced head and neck cancers, immune-based therapies have started to show results against these hard-to-treat tumors. Two immunotherapy drugs were approved in 2016 for use when standard treatments failed, and many other agents are being tested in clinical trials. Immunotherapies work by enhancing the body’s natural defenses […]

April 20, 2017
0
Cancer research , Care for adults , Prostate cancer
Online Tool Offers Guidance for Men with Non-Metastatic Prostate Cancer

Men diagnosed with non-metastatic prostate cancer now have access to a new tool on the TrueNTH USA website to help them prepare for their first meeting with a cancer physician. The tool, called Personal Patient Profile-Prostate (P3P), was created by Dana-Farber researchers and is now available to all men with […]

April 17, 2017
0
Cancer research , Risk and Prevention , Treatments and Procedures
How Does Radiation Raise the Risk of Other Cancers?

Along with chemotherapy, radiation therapy is a common method for treating cancer; about half of patients receive the therapy, which uses high-energy radiation to shrink tumors and kill cancer cells, during the course of their treatment. While radiation therapy is effective against cancer cells, it also leaves its mark on […]

April 14, 2017
0
Cancer research , Precision Cancer Medicine , Treatments and Procedures
What To Know About Precision Cancer Medicine [Infographic]

Precision cancer medicine is an evolving approach to cancer care that personalizes treatment based on each patient’s unique genetic mutations. Since 2011, Dana-Farber has used its Profile research project, in partnership with Brigham and Women’s Hospital and Boston Children’s Hospital, to gather adult and pediatric patients’ tumor tissues and detect […]

April 6, 2017
1
Cancer research , Multiple Myeloma
What’s New in Multiple Myeloma? [Webchat]

In a recent Facebook Live webchat, Jacob Laubach, MD, MPP, Clinical Director of the Jerome Lipper Multiple Myeloma Center, discussed the different ways that patients can be treated with multiple myeloma, as well as exciting avenues of treatment, such as combination therapy.

April 4, 2017
2
Cancer research , Hodgkin lymphoma , Immunotherapy , Lymphomas , Non-Hodgkin lymphoma
New Immunotherapy Therapy Approved for Lymphoma Patients

The Food and Drug Administration (FDA) approved a new kind of immunotherapy drug for adults and children with classical Hodgkin lymphoma who have relapsed after three or more prior lines of therapy. The approved drug, pembrolizumab (Keytruda), is part of a class of immunotherapy drugs called checkpoint inhibitors that block […]

March 28, 2017
0
Cancer research , Immunotherapy , Kidney cancer
What’s New in Immunotherapy for Kidney Cancer?

Kidney cancer is one of several cancers that has responded well to immunotherapy drugs, which can free the immune system from restraints that cancer cells can impose on it. The drug nivolumab (Opdivo), for example, which was recently approved, can extend survival in patients with metastatic kidney cancer after other […]

March 23, 2017
0
Cancer research , Immunotherapy , Melanoma
What’s New in Immunotherapy and Melanoma? [Webchat]

Cancer immunotherapy is a kind of cancer treatment that mobilizes the patient’s immune defenses to recognize and attack tumor cells. It is now the treatment of choice for many patients with advanced melanoma, according to Elizabeth I. Buchbinder, MD, a melanoma specialist at Dana-Farber. “Immunotherapy has taken off,” Buchbinder says, “There […]

March 14, 2017
1
Cancer research , Risk and Prevention
Firefighters and Cancer: Dana-Farber Scientists Investigate

A fire truck pulls into the truck bay and idles for a minute or two as a firefighter attaches tubing to filter the exhaust out of the station. The firefighter’s face may be close to the exhaust for 30 seconds while the tubing is attached. It’s a routine task, one […]

February 27, 2017
3
Acute lymphoblastic - ALL , Cancer research , Care for children , Leukemias , Research
Do Childhood Leukemia Patients with Down Syndrome Need Modified Therapy?

Because of their increased susceptibility to the toxicities of chemotherapy, should ALL patients with Down syndrome receive modified treatment to minimize this risk? Or should they be given the same treatment as other children with ALL, to minimize the chance for relapse?

February 17, 2017
0
Cancer research , General interest , Research
Which Countries Have the Highest Rates of the World’s Most Common Cancers? [INFOGRAPHIC]

Cancer occurs worldwide, and commonly – in 2012, there were an estimated 14.1 million new cancer cases globally, according to the World Cancer Research Fund. But not all cancers are created equally. Certain countries have higher rates of some cancers and lower of others, depending on a number of factors, […]

February 3, 2017
0
Breast cancer , Cancer research , Care for adults , Research , Treatments and Procedures
Who Needs Chemotherapy after Treatment for Early Breast Cancer?

Following surgery and/or radiation for early stage breast cancer, chemotherapy is sometimes given to eliminate remaining cancer cells that could cause trouble later. Traditionally, women have been more likely to undergo follow-up chemotherapy if clinical and pathological factors suggested a significant risk of recurrence, such as a larger tumor, higher […]

February 2, 2017
1
Cancer research , Immunotherapy , Research
Can a Serum Biomarker Predict Response to Immunotherapy?

This post originally appeared on Cancer Research Catalyst, a blog from the American Association of Cancer Research (AACR). By Srivani Ravoori, PhD Immunotherapy, particularly a class of immunotherapeutics called immune checkpoint inhibitors, has transformed the treatment of several types of cancer in recent years. So far, the U.S. Food and […]

January 26, 2017
1
Cancer research , Research
Why Is It Difficult to Pinpoint the Exact Cause of a Person’s Cancer?

A diagnosis of cancer always comes as a shock, and the patient naturally asks the physician, why did this happen? Is it something I did or didn’t do, or did I inherit it, or were chemicals in the environment to blame? “Why patients develop cancers is not well known,” explains […]

January 23, 2017
0
Cancer research
How Do I Find The Right Clinical Trial For Me?

Clinical trials are research studies that explore whether new treatments, diagnostic techniques, or disease-prevention strategies are safe and effective in patients. They may be an option when patients no longer benefit from standard therapies. They may also offer an alternative to standard therapies, particularly if the agent being tested is […]

January 17, 2017
0
Cancer research , Immunotherapy , Precision Cancer Medicine , Research , Risk and Prevention
Experts Forecast Cancer Research and Treatment Advances in 2017

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research. It was originally published Jan. 10, 2017. By Srivani Ravoori, PhD As we step into 2017, a big question looming in the minds of all stakeholders in the cancer research arena is: […]

January 10, 2017
0
Breast cancer , Cancer research , Research
Study Shows New Drugs Expose Vulnerability of Breast Tumors

“If it’s not broke, don’t fix it” may be a valid philosophy in general, but not in dealing with the molecular machinery of cancer cells. There, the applicable motto might be might be, “If it’s broke, keep it that way.” That’s the approach taken by a class of targeted drugs […]

December 20, 2016
0
Cancer research , General interest , Lung cancers , Risk and Prevention
Is Marijuana Use Connected to Cancer?

In November, four states – California, Massachusetts, Nevada, and Maine – passed measures legalizing marijuana for recreational use, bringing the total number of states with legal cannabis to eight, plus the District of Columbia. The vote in Maine was quite close and is expected to be challenged by opponents, but […]

December 15, 2016
4
Cancer research , General interest
21st Century Cures Act Will Support ‘Revolutionary’ Cancer Research

On Dec. 13, President Barack Obama signed into law the 21st Century Cures Act, legislation that includes significant funding to the National Institutes of Health (NIH) to further the Beau Biden Cancer Moonshot, and to the Food and Drug Administration (FDA) to speed the drug approval process. Laurie Glimcher, MD, […]

December 14, 2016
0
Cancer research , Care for adults , Metastatic breast cancer , Treatments and Procedures
A New Approach to Understanding Breast Cancer Treatment Resistance

By Srivani Ravoori, PhD, American Association for Cancer Research This post first appeared on the Cancer Today website. In a study presented Dec. 7 at the San Antonio Breast Cancer Symposium, researchers conducted genomic analysis of estrogen receptor (ER)-positive metastatic breast cancer samples that had become resistant to therapies. They found […]

December 9, 2016
1
Breast cancer , Cancer research , General interest , Treatments and Procedures
What Is Adjuvant Therapy?

Adjuvant therapies are drug treatments that breast cancer patients receive after surgery to prevent cancer from returning. These treatments may include chemotherapy, anti-estrogen therapy, or anti-HER2 therapy. Watch More: Young and Strong Program Helps Young Women With Breast Cancer Life After Inflammatory Breast Cancer “This is now a widely established […]

December 2, 2016
0
Cancer research , Gastrointestinal Cancer , Immunotherapy , Pancreatic cancer
Can Immunotherapy Help Patients with Pancreatic Cancer?

Patients with pancreatic cancer often ask Dana-Farber’s Brian Wolpin, MD, MPH, about immunotherapy, the rising star of cancer treatment that’s making impressive gains against many types of malignancies. Immunotherapy drugs, which mobilize the patient’s immune defenses to recognize and attack tumor cells, have worked against lethal cancers such as melanoma […]

November 30, 2016
0
Cancer research , General interest , Neuroendocrine/Carcinoid tumors
What Are Carcinoid Tumors?

Carcinoid tumors are rare, often slow-growing tumors that form from neuroendocrine cells found throughout the body. Carcinoid tumors most commonly arise in the gastrointestinal system, including the appendix, small intestine, or rectum, but may occur in other sites, including the lungs. In most cases, there is no clear cause of […]

November 25, 2016
1
Cancer research , Health and Wellness , Health Topics , Lung cancers
How to Quit Smoking: What We Know

Smoking cigarettes contributes to 80 percent of lung cancer deaths in women and 90 percent of lung cancer deaths in men, and it is estimated to have caused more than 130,000 deaths from the disease between 2005 and 2010. But smoking damage does not stop with lung cancer: the habit […]

November 17, 2016
0
Cancer research , Head and Neck Cancer , Immunotherapy
Use of Immunotherapeutic Expanded to Fifth Type of Cancer

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association of Cancer Research. It was originally published Nov. 15, 2016. By Karen Honey, PhD On Thursday, the U.S. Food and Drug Administration (FDA) announced that it had approved expanding the use of the immunotherapeutic nivolumab […]

November 15, 2016
4
Cancer research , Research , Risk and Prevention
What Are Tumor Markers?

Blood tests for the presence of substances called tumor markers can be helpful in diagnosing cancer and assessing how well treatment is working. But such tests alone generally can’t tell for certain whether someone has cancer or not. That’s why they are used in conjunction with other methods, such as […]

October 27, 2016
0
Bladder cancer , Cancer research , Immunotherapy
Immunotherapy Beats Chemotherapy for Advanced Bladder Cancer Patients

The immunotherapy drug pembrolizumab (Keytruda) is the first therapy of any kind to improve survival in patients whose metastatic bladder cancer worsened after treatment with platinum-based chemotherapy. Keytruda proved so much better than chemotherapy in this “second-line” use that an international clinical trial was halted when the advantage became apparent. […]

October 21, 2016
0
Cancer research , Ovarian cancer , Treatments and Procedures
Drug Prolongs Remissions in Some Relapsed Ovarian Cancers

Ed. note: Niraparib (Zejula) was approved by the U.S. Food and Drug Administration (FDA) on March 28, 2017, as a maintenance therapy for women with ovarian, fallopian tube, or primary peritoneal cancer. This post was originally published on Oct. 21, 2016. For women with relapsed ovarian cancer that responds to platinum-based […]

0
Cancer research , General interest , Research
What Can Be Learned from Clinical Trials that Fail?

When a clinical trial shows that a new treatment is no better than the standard, it can be disappointing. But such outcomes yield valuable, potentially lifesaving information. Trials can “fail” if the experimental therapy doesn’t work better than current treatments. These “negative” outcomes are important for several reasons. They can […]

October 14, 2016
0
Breast cancer , Cancer research , Care for adults , Treatments and Procedures
What Are Aromatase Inhibitors?

Aromatase inhibitors are drugs given to patients with hormone-receptor-positive breast cancer (HR+). They target the aromatase enzyme, which helps produce female hormones such as estrogen. Estrogen drives the growth of many HR+ tumors, and these drugs help control estrogen production, says Harold Burstein, MD, PhD, a breast cancer specialist in […]

October 6, 2016
0
Cancer Genetics , Cancer research
Genetics vs. Genomics: What’s the Difference?

Gene, genetics, genome, and genomics all are derived from a Greek word – gen – meaning birth or origin. Almost every aspect of health and disease is influenced in some way by the inherited information in cells, written in the chemical code of DNA and packaged in distinct units known […]

October 4, 2016
0
Cancer research , Ovarian cancer
Ovarian Cancer: State of the Science

By Ursula Matulonis, MD This is an exciting time for those of us engaged in research and patient care for ovarian cancer. As we’ve learned more about this cancer – its early formation, molecular machinery, and the body’s defenses against it – we’ve also come to understand its weaknesses. An […]

September 29, 2016
0
Cancer research , Immunotherapy , Research
What’s New in Cancer Immunotherapy?

Keeping up with progress in the field of cancer immunotherapy requires paying close attention. The number of approved drugs that help the body’s immune system fight cancer continues to grow, as does the list of different cancers in which immunotherapy is proving effective – in some cases yielding dramatically longer-lasting […]

September 27, 2016
1
Cancer research , Patient Stories, Adult
Taking Action: Why One Cancer Patient Walks

by John O’Hara One day, I was sitting in a Dana-Farber waiting room, and I looked around at all of the people waiting with me. They were someone’s mother, father, sister, brother, child, neighbor, or friend — people just like me. And they were all facing what I was facing, […]

September 23, 2016
0
Blood Cancer , Blood disorders , Cancer research , Research
The Genomics Behind Blood Cancers and Other Blood Disorders

Many of the secrets of why precancerous conditions sometimes become cancerous are hidden in cells’ genes. At Dana-Farber, researchers are collecting tissue samples to see if they can pry open those secrets and unlock new treatment options for certain types of blood cancers and other blood disorders. They’re also exploring […]

September 13, 2016
0
Cancer research , Esophageal cancer , Health and Wellness , Risk and Prevention
Do Hot Drinks Increase the Risk of Esophageal Cancer?

Based on a review of numerous scientific studies, the International Agency for Research in Cancer (IARC) recently concluded that routine consumption of “very hot” drinks probably raises the risk of esophageal cancer. The review, by a panel of 23 experts around the world, found that drinking beverages such as coffee […]

September 6, 2016
0
Cancer research , Care for adults , Patient Stories, Adult , Research
Precursor Blood Condition Patient Pays it Forward

When Lori Kauzlarich discovered that she had a precursor blood condition in August 2013, she sprang into action. “I was stunned,” she says. “But I decided to advocate for myself.” Precursor conditions are blood disorders that may evolve into cancers such as leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. They are […]

September 2, 2016
0
Cancer research , Endometrial (Uterine) cancer
What is the Latest Research in Endometrial Cancer?

For endometrial cancer, as for virtually every form of cancer, advances in genomics are transforming the understanding and treatment of this disease, which arises in the lining of the uterus or womb. As part of the Profile research project at Dana-Farber, Brigham and Women’s Hospital, and Boston Children’s Hospital, investigators […]

August 30, 2016
0
Cancer Genetics , Cancer research , Care for adults , Gastrointestinal Cancer , Pancreatic cancer
Can Pancreatic Cancer Be Inherited?

Most cases of pancreatic cancer develop for unknown reasons, but about 10 percent occur in families that have a strong history of the disease. That doesn’t mean that if you are a member of such a family you will develop pancreatic cancer, but rather that you are at a higher […]

August 17, 2016
1
Cancer research , Research , Risk and Prevention
How Does Cancer Spread?

Cancer is most dangerous when it has spread, or metastasized, from its original site in the body. A tumor that began as an isolated mass – often treatable by surgery and/or radiation therapy – can become a dispersed, much more difficult to treat, malignancy. For cancer to spread, several steps […]

August 10, 2016
0
Cancer research , Research , Treatments and Procedures
How Do PARP Inhibitors Work In Cancer?

PARPs (or Poly (ADP-ribose) polymerases)  are proteins that play an important role in the life of a cell. When a strand of the DNA double helix is broken or damaged, PARPs  act as a repair crew to help fix the damaged site, allowing the cell to live. For healthy cells […]

July 21, 2016
0
Blood Cancer , Cancer research , Treatments and Procedures
What Are Precursor Blood Conditions and How Are They Treated?

Precursor conditions are early phases of blood diseases that may develop into cancers such as lymphoma, leukemia, Waldenström’s macroglobulinemia, and multiple myeloma. Most people do not experience symptoms, and since doctors rarely screen for precursor conditions, they are often diagnosed after routine blood tests. “Many diagnoses are purely incidental,” says […]

July 15, 2016
0
Cancer research , Immunotherapy , Susan F. Smith Center , Treatments and Procedures
Fighting Women’s Cancers from Within

Traditionally, the war on cancer has been waged from the outside in, with therapies such as surgery, radiation, and drugs entering the body from external sources. For more than 100 years, however, a notion has persisted that the most formidable tool against cancer may come from within: the immune system. […]

June 27, 2016
0
Cancer research , Care for adults , Patient Stories, Adult
Individualized Clinical Trial Gives Patient with Rare Cancer Time to Celebrate

Kerri Antonuccio marked her 40th birthday this spring with a fresh lease on life. For the first time since 2012, she didn’t feel too sick from cancer treatment to enjoy her big day. She was also able to travel to Mexico and serve as matron of honor at her sister’s […]

June 20, 2016
2
Cancer research , Diet and Nutrition , Risk and Prevention
Can Vitamin D Reduce Cancer Risk?

Scientific evidence that vitamin D can help lower the risk of cancer development, as well as the risk of metastasis or recurrence, has been mixed. But several new studies point toward such a connection for certain cancers. Numerous population-tracking studies over the years have shown that higher intake or blood […]

June 17, 2016
2
Cancer research , Immunotherapy , Melanoma , Research
ASCO 2016 Update: Immunotherapy and Melanoma

As one of the hottest topics in cancer research today, immunotherapy took center stage at the 2016 American Society of Clinical Oncology meeting in Chicago. Harold J. Burstein, MD, PhD, a breast oncologist in the Susan F. Smith Center for Women’s Cancers at Dana-Farber Cancer Institute, recently sat down with […]

June 15, 2016
1
Cancer research , Precision Cancer Medicine
How Can Bioinformatics Help Advance Precision Cancer Care?

Scattered amongst the letters of genetic code in a tumor cell are telltale mutations and DNA alterations that spur its malignant activity. But there are billions of letters of code and each patient’s cancer is different, with its own particular genetic changes. These changes may dictate how it behaves, how […]

May 27, 2016
0
Cancer research , Care for adults , Patient Stories, Adult
From Cancer Researcher to Patient and Back

By Katherine Walsh When faced with something as scary and life-changing as a cancer diagnosis, the way we see the world drastically changes. My story is a literal shift – from cancer researcher to leukemia patient, and a very sick one at that. My world came to a screeching halt […]

May 23, 2016
0
Cancer research , Health and Wellness , Risk and Prevention
Can Stress Affect Cancer?

Stress is generally defined as a condition in which the body or mind is placed under strain or tension. Stress is a normal part of life. In fact, studies show it to be a necessary part of life, prompting us to adapt and become more resilient. But if it becomes […]

May 19, 2016
2
Cancer research , Care for adults
A Behind the Scenes Look at the People Helping to Usher in New Cancer Therapies: A Nurse’s Story

This post originally appeared on HuffPost Impact. By Joan Lucca, RN, MSN Nearly four decades ago, I became a nurse and dedicated my life’s work to the care and comfort of patients. The ‘70s was a decade of change and opportunity as doors began to open for women in emerging […]

May 17, 2016
0
Cancer research , Rectal cancer , Treatments and Procedures
Team Care and Positive Attitude Help Rectal Cancer Patient Through Treatment

Back when D.N. Chadha, MA, was a pharmaceutical executive meeting with Jeffrey Meyerhardt, MD, MPH, in 2002, he never imagined he’d see the physician years later – this time for rectal cancer treatment. “The name rang a bell, and as soon as I saw him, I knew,” says Chadha, 74, […]

May 16, 2016
0
Cancer research , Treatments and Procedures
What Is a Liquid Biopsy?

A traditional biopsy is a test in which a piece of tissue is removed from a patient for analysis in a laboratory. A pathologist examines the tissue under a microscope, noting the shape, structure, and internal activity of the cells to determine whether the cells are cancerous and, if so, […]

April 20, 2016
0
Cancer research , Immunotherapy
How Scientists Aim to Expand Immunotherapy Options for Cancer Patients

This post also appeared on the NERD (Novartis Explores Research & Development) blog. By Eric Bender Fighting cancer with immunotherapy has revolutionized treatment for some patients. Emphasize “some.” For most patients, drugs targeting the immune system to attack their tumors aren’t an option. This could change in the near future. […]

April 14, 2016
0
Cancer research , Care for adults , Stem cell/Bone marrow transplant
FDA Approval of Defibrotide Brightens Outlook for Stem Cell Transplant Patients

Patients and Dana-Farber researchers alike welcomed this week’s Food and Drug Administration (FDA) approval of a new drug for a potentially fatal side effect of stem cell transplants. The approval means patients can receive the drug, defibrotide, as standard therapy for hepatic veno-occlusive disease (VOD) of the liver, a dangerous […]

March 31, 2016
0
Cancer research , Immunotherapy , Rectal cancer
Can We Treat Colorectal Cancer With Immunotherapy?

This post originally appeared on Cancer Research Catalyst, the official blog of the American Association for Cancer Research (AACR). It is posted here with minor edits. March is Colorectal Cancer Awareness Month. About 134,490 people are estimated to be diagnosed with and about 49,190 are expected to die from colorectal […]

March 21, 2016
0
Cancer research , Care for adults , Patient Stories, Adult , Precision Cancer Medicine
How Precision Cancer Care Saved a Life

Ronaldo de Oliveira was close to death. The 33-year-old father of two young children had been diagnosed with myeloid sarcoma, a rare form of leukemia that worsened despite treatment with six different chemotherapy regimens. His wife pleaded with his oncologist, Richard Stone, MD, director of the Adult Leukemia Program at […]

March 18, 2016
0
Cancer research , Diet and Nutrition , Health Topics , Risk and Prevention
How Does Alcohol Cause Cancer?

This blog post was originally published on the Cancer Research UK science blog. It is reposted here with minor edits.   In a cabinet in London’s British Museum nestles a 5,300 year-old wedged-shaped tablet called a cuneiform. On its surface is scrawled one of the earliest forms of written language […]

March 3, 2016
0
Cancer research , Immunotherapy
What Makes Cancer Cells Different from Normal Cells?

Although they may seem like foreign invaders, cancer cells develop out of normal body cells and tissues. Over a period of years, damage to the DNA of healthy cells disrupts their orderly growth, leading to the formation of malignant tumors. Cancer cells may contain thousands of mutations – alterations in […]

March 2, 2016
0
Cancer research , Melanoma , Research
The Cell that Caused Melanoma: Cancer’s Surprise Origins, Caught in Action

This post originally appeared on Vector, Boston Children’s Hospital’s science and clinical innovation blog. It’s long been a mystery why some of our cells can have mutations associated with cancer, yet are not truly cancerous. Now researchers have, for the first time, watched a cancer spread from a single cell […]

February 17, 2016
2
Blood Cancer , Cancer research
The Latest Research in Multiple Myeloma, Leukemia and Other Blood Cancers

The last two years have been very exciting for blood cancer research; many new targeted therapies and immunotherapies are improving treatment outcomes for patients with lymphoma, leukemia and multiple myeloma. “We’re starting to see a lot of hematologic malignancies benefit from immunotherapy,” says Irene Ghobrial, MD. “The excitement is there […]

February 11, 2016
0
Cancer research , Care for adults , Immunotherapy , Treatments and Procedures
What Are the Side Effects of Immunotherapy?

New drugs that stimulate the patient’s immune system to attack tumors have achieved some dramatic and long-lasting benefits in several forms of cancer. A few drugs are already approved for wide use and many more are in the research pipeline. Because these immunotherapy agents work differently than chemotherapy, the side […]

February 10, 2016
6
Cancer research , Care for children , Patient Stories, Pediatric , Precision Cancer Medicine
In Precision Medicine, Pioneering Young Patient Teaches Veteran Doctor

Allison Schablein seems an unlikely candidate to teach medicine to Mark Kieran. She’s an 8–year-old New Hampshire second grader who loves basketball, hip hop, acrobatic dancing and jewelry. He’s a pediatric neuro-oncologist with a PhD in molecular biology, not to mention decades of clinical and research experience. But teach Kieran, […]

January 28, 2016
0
Cancer research , Cervical Cancer , Immunotherapy
Targeted Therapy, Immunotherapy Among Top Research Areas for Cervical Cancer

Cancers of the cervix are diagnosed in more than 12,000 women in the United States every year. Worldwide, the annual tally of new cases reaches more than half a million. The biggest advance against the disease in recent years has come in the area of prevention. Vaccination against the human […]

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Cancer research , Care for adults , Chronic lymphocytic - CLL , Treatments and Procedures
A New Cancer Drug — in the Nick of Time

When Roy Jann was diagnosed with cancer in 2013, it never crossed his mind that he would be a model for the life-saving potential of venetoclax, a new type of cancer drug that had recently entered human testing. The first inkling that something was amiss had come a few weeks […]

January 15, 2016
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